Seong Joon, Je Creeth, Gr Burnett, E Sanchez, M Araga, West Nicola
Clinical Trials Group, Bristol Dental School, University of Bristol, Lower Maudlin Street, Bristol, BS1 2LY, United Kingdom.
Haleon, Weybridge, Surrey, KT13 0DE, United Kingdom.
J Dent. 2025 May;156:105643. doi: 10.1016/j.jdent.2025.105643. Epub 2025 Mar 4.
This study was designed to evaluate the effectiveness of a multi-step oral hygiene intervention among removal partial denture (RPD) wearers.
A 12-week, single-blind, randomised, 2-armed, parallel-group, controlled trial was conducted with 49 RPD-wearing participants with mild-moderate gingivitis. The intervention group received stannous fluoride toothpaste, sodium fluoride mouth rinse, and an antibacterial denture cleanser foam. They were given detailed instructions on product usage. The control group continued with their usual oral hygiene regimen. Gingival health, denture cleanliness, and oral hygiene indices were assessed at baseline, 6, and 12 weeks.
48 participants completed the study, (one withdrawal due to concomitant medication). The intervention group reported 12.5 % adverse events, with no events reported in the no-intervention group. Compliance rates were high for toothbrushing (99.4 %), mouth rinse use (99.4 %), and denture cleaning (99.3 %). Significant improvements were observed for the intervention group in bleeding index, modified gingival index, and Turesky Plaque Index at both weeks 6 and 12 (p < 0.0001). Denture cleanliness also significantly improved, with lower Partial Denture Cleanliness Index scores at weeks 6 (p = 0.0039) and 12 (p < 0.0001). Overall, the intervention group showed consistently superior outcomes compared to the control, with significant differences in all plaque and gingivitis measures (p < 0.0001).
This study highlighted the efficacy of a multi-step oral hygiene intervention in improving oral health outcomes among RPD-wearers with mild-moderate gingivitis. Findings from this study may inform evidence-based recommendations for optimal oral healthcare in this population, benefiting both patients and oral healthcare professionals.
This study demonstrated that a multi-step intervention, including three specific oral hygiene products and education, can significantly improve oral health outcomes for removable partial denture wearers with mild-moderate gingivitis. These findings offer practical insights for enhancing oral hygiene practices and gingival health in this patient population.
本研究旨在评估多步骤口腔卫生干预措施对可摘局部义齿（RPD）佩戴者的有效性。
对49名患有轻中度牙龈炎的RPD佩戴者进行了一项为期12周的单盲、随机、双臂、平行组对照试验。干预组使用含氟牙膏、含氟漱口水和抗菌义齿清洁泡沫，并给予详细的产品使用说明。对照组继续其常规口腔卫生方案。在基线、第6周和第12周评估牙龈健康状况、义齿清洁度和口腔卫生指数。
48名参与者完成了研究（1人因同时服用其他药物退出）。干预组报告了12.5%的不良事件，无干预组未报告不良事件。刷牙（99.4%）、使用漱口水（99.4%）和义齿清洁（99.3%）的依从率很高。在第6周和第12周时，干预组的出血指数、改良牙龈指数和Turesky菌斑指数均有显著改善（p < 0.0001）。义齿清洁度也显著提高，在第6周（p = 0.0039）和第12周（p < 0.0001）时，局部义齿清洁指数得分更低。总体而言，与对照组相比，干预组的结果始终更优，在所有菌斑和牙龈炎指标上均有显著差异（p < 0.0001）。
本研究强调了多步骤口腔卫生干预措施在改善患有轻中度牙龈炎的RPD佩戴者口腔健康状况方面的有效性。本研究结果可为该人群最佳口腔保健的循证建议提供参考，使患者和口腔保健专业人员均受益。
本研究表明，包括三种特定口腔卫生产品和教育的多步骤干预措施，可显著改善患有轻中度牙龈炎的可摘局部义齿佩戴者的口腔健康状况。这些发现为改善该患者群体的口腔卫生习惯和牙龈健康提供了实用见解。
