Algie T A, Seth A, Barbenel J C, Galloway D J, Gray W M, Spence A A
Br J Anaesth. 1985 Jun;57(6):621-3. doi: 10.1093/bja/57.6.621.
Following a paravertebral surgical incision, mature, female rats under ether anaesthesia were exposed to either 3% nitrous oxide, continuously for 48 h, or 50% nitrous oxide, 4 h each day for 7 days. For each exposure group, a similar number of rats was exposed to atmospheres containing no nitrous oxide. Wound healing was assessed by measurement of the breaking strengths of wound samples. No statistically significant influence on breaking strength could be attributed to nitrous oxide following either exposure sequence.
在椎旁手术切口后，将处于乙醚麻醉下的成年雌性大鼠持续暴露于3%的一氧化二氮中48小时，或每天暴露于50%的一氧化二氮中4小时，共7天。对于每个暴露组，将数量相似的大鼠暴露于不含一氧化二氮的环境中。通过测量伤口样本的断裂强度来评估伤口愈合情况。两种暴露顺序后，一氧化二氮对断裂强度均无统计学上的显著影响。
