Chopra Arvind, Mathew Ashish Jacob, Handa Rohini, Parshuram Ghorpade Ravi, Sanjeev Sarmukaddam, Lagu-Joshi Vaijayanti, Gauri Liyakat, Asma Rahim, Paul Binoy, Kumar Datta, Pal Sarvajeet, Sarika Chaturvedi, Bhaskar Thakuria, Mahajan Annil, Singh Romi, Ghosh Alakendu, Tapas Kumar, Rajendran C P, Venugopalan Anuradha, Saluja Manjit, Mahendranath K
Center for Rheumatic Diseases, Pune, India.
Christian Medical College, Vellore, India.
Int J Rheum Dis. 2025 Mar;28(3):e70163. doi: 10.1111/1756-185X.70163.
Several countries have participated in WHO COPCORD. The Global Disease Burden program (GBD) reports selected MSK disorders. We used a COPCORD India protocol to estimate the national burden of MSK disorders.
Trained paramedics used standard questionnaires to screen the population and identify respondents with current and/or past MSK pain (non-traumatic) in 12 survey sites (8 rural); cross-sectional design and prospective data. Several standard measures were recorded; MSK pain was self-reported (on human manikin). The site rheumatologist examined each respondent and provided a clinical diagnosis. Pooled data (anonymized) from all sites was analyzed using standard statistical software. Standardized point prevalence rates (adjusted to Indian Census) and odds ratios (risk factors) were calculated: 95% confidence intervals in parentheses.
56 548 population (60% rural, response rate > 70%) was screened; 10 273 respondents (18%, 65% women). The prevalence of MSK pain was 16.14 (14.2, 18.3) and higher in the rural population (20% vs. 10.3%); rheumatoid arthritis 0.34%, undifferentiated inflammatory arthritis 0.22%, spondyloarthritis 0.23%, osteoarthritis 4.39%, Gout 0.05%, chikungunya arthritis 1.2%. Non-specific arthralgias, soft tissue pains, and degenerative arthritis were dominant disorders; 12% of respondents reported inflammatory arthritis. Significant risk factors associated with MSK pain included female gender, poor literacy, non-vegetarian diet, chronic non-MSK illness, past trauma, and tobacco use. Limitations included non-random selection, clinical diagnosis, and limited investigations. However, in comparison to GBD, the COPCORD outcome seemed all-inclusive and clinically meaningful.
The high prevalence of MSK pain and arthritis indicates a huge disease burden in India and prioritizes the need for a national control program.
多个国家参与了世界卫生组织社区导向基层医疗疼痛协作计划(WHO COPCORD)。全球疾病负担项目(GBD)报告了选定的肌肉骨骼疾病。我们采用印度COPCORD方案来估计肌肉骨骼疾病的全国负担。
经过培训的医护辅助人员使用标准问卷对人群进行筛查,并在12个调查地点(8个农村地区)识别出目前和/或过去有肌肉骨骼疼痛(非创伤性)的受访者;采用横断面设计和前瞻性数据。记录了多项标准指标;肌肉骨骼疼痛由受访者根据人体模型自行报告。各调查地点的风湿病学家对每位受访者进行检查并给出临床诊断。使用标准统计软件对所有地点汇总的数据(匿名)进行分析。计算标准化点患病率(根据印度人口普查数据调整)和比值比(风险因素):括号内为95%置信区间。
共筛查了56548人(60%为农村人口,应答率>70%);10273名受访者(占18%,65%为女性)。肌肉骨骼疼痛的患病率为16.14(14.2,18.3),农村人口中的患病率更高(20%对10.3%);类风湿关节炎为0.34%,未分化炎性关节炎为0.22%,脊柱关节炎为0.23%,骨关节炎为4.39%,痛风为0.05%,基孔肯雅热关节炎为1.2%。非特异性关节痛、软组织疼痛和退行性关节炎是主要疾病;12%的受访者报告有炎性关节炎。与肌肉骨骼疼痛相关的显著风险因素包括女性、文化程度低、非素食饮食、慢性非肌肉骨骼疾病、既往创伤和吸烟。局限性包括非随机选择、临床诊断和有限的检查。然而,与全球疾病负担项目相比,COPCORD的结果似乎更全面且具有临床意义。
肌肉骨骼疼痛和关节炎的高患病率表明印度存在巨大的疾病负担,因此需要制定全国性的控制计划。