Konstantinou Christos S, Sfairopoulos Dimitrios, Zekios Konstantinos, Letsas Konstantinos P, Korantzopoulos Panagiotis
First Department of Cardiology, University of Ioannina Medical School, Ioannina, Greece.
Arrhythmia Unit, Onassis Cardiac Surgery Center, Athens, Greece.
J Innov Card Rhythm Manag. 2025 Feb 15;16(2):6177-6183. doi: 10.19102/icrm.2025.16026. eCollection 2025 Feb.
Brugada phenocopy (BrP) is the electrocardiographic appearance of a Brugada pattern due to various reversible causes that is completely resolved after the correction of the underlying abnormalities. In this short communication, we describe a 56-year-old man who had a transient BrP induced by hyponatremia due to thiazide diuretic therapy. A detailed review of the literature revealed that hyponatremia represents an uncommon cause of BrP while, in many of the published cases, concomitant electrolyte disturbances such as hyperkalemia were present. However, even isolated hyponatremia may provoke a BrP. Clinicians should be aware of this rare cause of BrP, which is reversible and has a favorable outcome.
Brugada 综合征拟表型（BrP）是指由于各种可逆性病因导致出现 Brugada 图形的心电图表现，在纠正潜在异常后可完全消失。在本简短通讯中，我们描述了一名 56 岁男性，其因噻嗪类利尿剂治疗导致低钠血症而诱发了短暂性 BrP。对文献的详细回顾显示，低钠血症是 BrP 的一种罕见病因，而在许多已发表的病例中，同时存在高钾血症等电解质紊乱。然而，即使是孤立的低钠血症也可能引发 BrP。临床医生应意识到这种 BrP 的罕见病因，它是可逆的且预后良好。
