David Matthias, von Ahsen Nicolas, Alkatout Ibrahim, Bahlmann Franz, Fehr Peter Martin, Hancke Katharina, Hiller Ruth, Hodel Markus, Hoopmann Markus, Korell Matthias, Manegold-Brauer Gwendolin, Markfeld-Erol Filiz, Müller Annette M, Oppelt Peter, Rudnik-Schöneborn Sabine, Sonntag Barbara, Starkmuth Susanne, Valet Axel, Wallwiener Stephanie, Weichert Jan, Witzel Simone, Becker Sven
Klinik für Gynäkologie, Campus Virchow-Klinikum, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Institut für Labormedizin, Klinikum Links der Weser, Gesundheit Nord Klinikverbund Bremen gGmbH, Bremen, Germany.
Geburtshilfe Frauenheilkd. 2025 Mar 5;85(3):282-310. doi: 10.1055/a-2466-2778. eCollection 2025 Mar.
This guideline aims to improve and standardize the diagnostic and therapeutic approaches for different types of miscarriages, pregnancies of unclear localization, and ectopic pregnancies in the 1st trimester. In accordance with the requirements for an S2k-guideline, this guideline was compiled following a search of the literature, and the various recommendations and statements were formally agreed upon by an interdisciplinary group of representative experts from Germany (DGGG, etc.), Austria (OEGGG) and Switzerland (SGGG) who met up several times under the aegis of the German Society for Gynecology and Obstetrics ( , DGGG). The guideline provides 129 recommendations on clinical, laboratory-based, ultrasonographical, pathomorphological and genetic diagnostics and describes and assesses different therapeutic options in terms of their success and complication rates and the continued fertility of the patient as well as aspects of the grieving process and coming to terms with the loss after an early loss of pregnancy.
本指南旨在改善和规范孕早期不同类型流产、妊娠部位不明及异位妊娠的诊断和治疗方法。根据S2k指南的要求，本指南在文献检索的基础上编写而成，各项建议和声明由来自德国（德国妇科和产科学会等，DGGG）、奥地利（奥地利妇科和产科学会，OEGGG）和瑞士（瑞士妇科和产科学会，SGGG）的跨学科代表专家小组正式商定，这些专家在德国妇科和产科学会（DGGG）的支持下多次会面。该指南提供了129条关于临床、实验室、超声、病理形态学和基因诊断的建议，并从成功率、并发症发生率、患者的持续生育能力以及悲伤过程和孕早期流产后接受流产的各个方面描述和评估了不同的治疗选择。
