Melese Kasech, Alemu Tesfaye, Desalegn Asnake
Ethiopian Institutes of Agricultural Research EIAR, Debre Zeit Agricultural Research Center, Bishoftu, Ethiopia.
College of Natural and Computational Sciences, Department of Microbial, Cellular and Molecular Biology, Addis Ababa University, Addis Ababa, Ethiopia.
Braz J Microbiol. 2025 Jun;56(2):1333-1343. doi: 10.1007/s42770-024-01593-7. Epub 2025 Mar 7.
The gut microbiome, consisting of a diverse community of beneficial bacteria, supports broiler health and performance. This study aimed to assess the impact of probiotic lactic acid bacteria supplementation on growth performance, blood parameters, and antibody response in broiler chickens. The experiment involved 108 Cobb 500 breed chicks, which were allocated into three groups: T1 (received basal diets + L. reuteri at 1 × 10⁸ CFU/mL), T2 (received basal diets + P. pentosaceus at 1 × 10⁸ CFU/mL), and T3 (control group receiving only basal diets). The chicks were assigned to these groups randomly, following a completely randomized design. The results showed that the broiler groups supplemented with either L. reuteri or P. pentosaceus probiotics exhibited significant improvements (p < 0.05) in body weight, weight gain, and feed conversion ratio throughout the study. There were no significant differences (p > 0.05) in total protein and albumin levels. At the same time, cholesterol levels were lower in the L. reuteri and P. pentosaceus-treated groups compared to the control group. Furthermore, the hemagglutination inhibition titer of Newcastle disease was significantly (p < 0.05) higher in the groups supplemented with L. reuteri and P. pentosaceus. The study also found that the lymphoid organ weight/body weight ratio was significantly higher in the L. reuteri and P. pentosaceus groups. In conclusion, the oral administration of the probiotic strains L. reuteri DSM 20016T and P. pentosaceus DSM 20206 to broiler chickens improved growth performance, reduced blood cholesterol levels, and enhanced immune function. These findings indicate that these lactic acid bacteria could be beneficial as both immunomodulators and growth promoters in broiler production.
肠道微生物群由多种有益细菌组成，对肉鸡的健康和生长性能具有支持作用。本研究旨在评估补充益生菌乳酸菌对肉鸡生长性能、血液参数和抗体反应的影响。实验涉及108只科宝500品种雏鸡，分为三组：T1组（接受基础日粮+1×10⁸CFU/mL罗伊氏乳杆菌）、T2组（接受基础日粮+1×10⁸CFU/mL戊糖片球菌）和T3组（对照组仅接受基础日粮）。雏鸡按照完全随机设计随机分配到这些组中。结果表明，在整个研究过程中，补充罗伊氏乳杆菌或戊糖片球菌益生菌的肉鸡组在体重、体重增加和饲料转化率方面均有显著改善（p<0.05）。总蛋白和白蛋白水平无显著差异（p>0.05）。同时，与对照组相比，罗伊氏乳杆菌和戊糖片球菌处理组的胆固醇水平较低。此外，补充罗伊氏乳杆菌和戊糖片球菌的组中新城疫血凝抑制效价显著更高（p<0.05）。该研究还发现，罗伊氏乳杆菌和戊糖片球菌组的淋巴器官重量/体重比显著更高。总之，给肉鸡口服罗伊氏乳杆菌DSM 20016T和戊糖片球菌DSM 20206可改善生长性能、降低血液胆固醇水平并增强免疫功能。这些发现表明，这些乳酸菌作为免疫调节剂和生长促进剂在肉鸡生产中可能是有益的。
