植入对左心室辅助装置聚氨酯隔膜力学性能的影响。

Effects of implantation on the mechanical properties of the polyurethane diaphragm of left ventricular assist devices.

作者信息

Hayashi K, Matsuda T, Takano H, Umezu M, Taenaka Y, Nakamura T

出版信息

Biomaterials. 1985 Mar;6(2):82-8. doi: 10.1016/0142-9612(85)90068-7.

Abstract

Tensile properties of blood pump diaphragms made from a segmented polyether polyurethane (Toyobo TM5) were studied after implanting in goats for variable periods of time up to 72 days. The implantation decreased the tensile strength and ultimate elongation at break, while the elastic modulus increased very slightly. These changes in the strength and ductility were primarily caused by the contact of material with blood rather than by the mechanical fatigue of material. Mechanical stability was greatly improved by removing residual oligomers from the material by a refining procedure. The refined polyurethane has characteristics favourable for blood pump applications.

摘要

对由分段聚醚聚氨酯（东洋纺TM5）制成的血泵隔膜在山羊体内植入长达72天的不同时间段后的拉伸性能进行了研究。植入后，拉伸强度和断裂伸长率降低，而弹性模量略有增加。强度和延展性的这些变化主要是由材料与血液的接触引起的，而非材料的机械疲劳。通过精炼程序去除材料中的残留低聚物，可大大提高机械稳定性。精炼后的聚氨酯具有有利于血泵应用的特性。