Katayama Y, Becker D P, Hayes R L
Brain Res. 1985 Jun 3;335(2):392-5. doi: 10.1016/0006-8993(85)90502-5.
Afferent-induced primary afferent depolarization (PAD) was depressed for 2-5 min following concussive head injury in the cat, as assessed by dorsal root potentials and augmentation of antidromic dorsal root potentials, both evoked by stimulation of adjacent dorsal roots. These changes in PAD were abolished by spinal cord transection but not affected by midpontine transection. Spontaneous dorsal root potentials, resting amplitudes of antidromic dorsal root potentials and reductions of antidromic dorsal root potentials following tetanic root stimulation were not substantially altered by injury. These findings suggest that concussive head injury depresses spinal interneuronal transmission by neurally mediated processes involving the bulbar brainstem.
通过刺激相邻背根诱发的背根电位和逆向背根电位增强来评估，猫脑震荡损伤后传入诱导的初级传入去极化（PAD）在2 - 5分钟内受到抑制。脊髓横断可消除PAD的这些变化，但中脑桥横断对其无影响。损伤并未显著改变自发背根电位、逆向背根电位的静息幅度以及强直根刺激后逆向背根电位的降低。这些发现表明，脑震荡损伤通过涉及延髓脑干的神经介导过程抑制脊髓中间神经元的传递。
