Meyers P A, Potter V P, Wollner N, Exelby P
Cancer. 1985 Jul 15;56(2):259-61. doi: 10.1002/1097-0142(19850715)56:2<259::aid-cncr2820560209>3.0.co;2-1.
In the last 5 years we have seen six cases of bowel perforation during initial therapy for childhood non-Hodgkin's lymphoma (NHL). Perforation occurred only in patients with Stage III or IV disease. It occurred in patients without clinically detectable mural disease of bowel. Children who suffered bowel perforation had a worse outcome than those who did not, but two of the six patients described have gone on to long-term disease-free survival more than 2 years from completion of their treatment.
