Gaul B L, Stewart M E, Downing D T
Comp Biochem Physiol B. 1985;80(3):431-5. doi: 10.1016/0305-0491(85)90267-6.
The time course of sebum secretion in the guinea-pig (Cavia porcellus) was determined by intradermal injection of [1-14C]acetate followed by daily collection of the skin surface lipids at the injection site. The skin surface lipids reached a peak of radioactivity at 5-6 days, indicating that this is the time which elapses between the synthesis of sebum and the surface excretion of the sebaceous lipids. Of the three major skin surface lipid components, the sterol esters (25%) and the wax diesters (25%) showed similar peaks of radioactivity after labelling, but the glycerol ether diesters (30%) showed no radioactivity at any time, suggesting that this lipid is not produced in the skin.
通过皮内注射[1-¹⁴C]乙酸盐，随后每天收集注射部位的皮肤表面脂质，测定了豚鼠（豚鼠）皮脂分泌的时间进程。皮肤表面脂质在5-6天时达到放射性峰值，这表明这是皮脂合成与皮脂腺脂质表面排泄之间经过的时间。在三种主要的皮肤表面脂质成分中，甾醇酯（25%）和蜡二酯（25%）在标记后显示出相似的放射性峰值，但甘油醚二酯（30%）在任何时候都没有放射性，这表明这种脂质不是在皮肤中产生的。
