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巴基斯坦15至49岁城乡妇女妊娠丢失的预测因素。

Predictors of pregnancy loss among urban and rural women aged 15 to 49 years in Pakistan.

作者信息

Samuel Kevin George, Kandala Ngianga-Bakwin, Ryan Bridget L, Thind Amardeep

机构信息

Department of Epidemiology and Biostatistics, Western University, London, ON, Canada.

Departments of Family Medicine and Medicine, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.

出版信息

BMC Public Health. 2025 Mar 10;25(1):950. doi: 10.1186/s12889-025-22165-w.

Abstract

BACKGROUND

The burden of pregnancy loss remains high in low- and middle-income countries like Pakistan. The Every Newborn Action Plan (ENAP) aims to decrease the stillbirth rate to 12 per 1000 total births by 2030, in every country. Current estimates indicate that Pakistan is unlikely to achieve this ENAP target, as the stillbirth rate stands at 30.6 per 1000 total births.

METHODS

This study used the 2019 Pakistan Maternal Mortality Survey to identify the community-level, sociodemographic, maternal, environmental, and health services factors that are associated with pregnancy loss. Due to characteristic differences in urban and rural communities, separate analyses were carried out for ever-married women of 15 to 49 years. Mixed effects negative binomial regression was used to analyze the urban (n = 5,887) and rural (n = 7,136) samples of women who reported at least one pregnancy.

RESULTS

The separate analyses found the factors associated with pregnancy loss to vary between urban and rural areas. In urban areas, pregnancy loss was associated with maternal education, maternal age, current marital status, and sanitation facility type. In rural areas, pregnancy loss was associated with region of residence, wealth index, maternal age, current marital status, drinking water source, cooking fuel type, and sanitation facility type.

CONCLUSION

This study carries significant implications for alleviating the burden of pregnancy loss in Pakistan, in line with ENAP objectives. The separate analyses provide a novel perspective regarding the factors influencing pregnancy loss in urban and rural areas, allowing for targeted interventions.

摘要

背景

在巴基斯坦等低收入和中等收入国家,流产负担仍然很高。《每一名新生儿行动计划》(ENAP)旨在到2030年在每个国家将死产率降至每1000例总出生12例。目前的估计表明,巴基斯坦不太可能实现这一ENAP目标,因为死产率为每1000例总出生30.6例。

方法

本研究利用2019年巴基斯坦孕产妇死亡率调查,确定与流产相关的社区层面、社会人口、孕产妇、环境和卫生服务因素。由于城乡社区存在特征差异,对15至49岁的已婚妇女进行了单独分析。采用混合效应负二项回归分析报告至少一次怀孕的城市(n = 5887)和农村(n = 7136)妇女样本。

结果

单独分析发现,与流产相关的因素在城乡之间存在差异。在城市地区,流产与孕产妇教育、孕产妇年龄、当前婚姻状况和卫生设施类型有关。在农村地区,流产与居住地区、财富指数、孕产妇年龄、当前婚姻状况、饮用水源、烹饪燃料类型和卫生设施类型有关。

结论

本研究对于按照ENAP目标减轻巴基斯坦的流产负担具有重要意义。单独分析为影响城乡流产的因素提供了新的视角,有助于进行有针对性的干预。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb22/11895280/938d102bec97/12889_2025_22165_Fig1_HTML.jpg

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