Chest. 1985 Jul;88(1):136-8. doi: 10.1378/chest.88.1.136.
The participants in the workshop reached unanimous consensus that as an investigative tool, BAL has enormous potential for extending knowledge of the immunopathogenesis of asthma. When utilized according to these guidelines, maximum knowledge may be gained with minimal risks to study subjects. However, we wish to emphasize that the extent to which the safety of the procedure applies to those asthmatic subjects with more symptoms and an FEV1 of less than 60 percent of predicted remains to be established by carefully controlled clinical investigations.
研讨会上的参与者一致认为，作为一种研究工具，支气管肺泡灌洗术在拓展哮喘免疫发病机制知识方面具有巨大潜力。按照这些指南使用时，在给研究对象带来最小风险的情况下可获得最大程度的知识。然而，我们希望强调的是，该操作的安全性在多大程度上适用于那些症状较多且第一秒用力呼气容积（FEV1）低于预计值60%的哮喘患者，仍有待通过严格对照的临床研究来确定。
