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“观察等待”作为小儿Rathke裂囊肿卒中的一种治疗选择:一例报告

''Wait and See'' as a Treatment Option for a Rathke's Cleft Cyst Apoplexy in Pediatric Population: A Case Report.

作者信息

Rouf Siham, Yaqoubi Latifa, Latrech Hanane

机构信息

Department of Endocrinology Diabetology and Nutrition, Mohammed VI University Hospital, Faculty of Medicine and Pharmacy of Oujda, Mohamed the First University, Oujda, Morocco.

Laboratory of Epidemiology, Clinical Research and Public Health, Faculty of Medicine and Pharmacy of Oujda, Mohammed the First University, Oujda, Morocco.

出版信息

Int J Endocrinol Metab. 2024 Mar 16;22(1):e143939. doi: 10.5812/ijem-143939. eCollection 2024 Jan.

DOI:10.5812/ijem-143939
PMID:40065848
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11892514/
Abstract

INTRODUCTION

Rathke cleft cyst apoplexy is exceedingly rare, particularly in infants. The most prevalent clinical manifestations include headaches, visual field defects, and endocrine dysfunction. Treatment options range from surgery to conservative methods, taking into consideration the balance of benefits and risks, especially during critical life stages such as childhood.

CASE PRESENTATION

We present the case of a 12-year-old boy admitted due to the recent onset of headaches and diabetes insipidus. Magnetic resonance imaging revealed Rathke cleft cyst apoplexy. Given the absence of compressive symptoms in a child at the early stages of puberty and without abnormalities in basic endocrine tests, a conservative strategy was employed, involving regular clinical, biological, and radiological follow-ups. The child experienced normal puberty without any endocrine deficiencies except for a partial growth hormone deficiency.

CONCLUSIONS

For clinically asymptomatic children diagnosed with Rathke's cleft cyst apoplexy, adopting a conservative management approach is recommended, provided there is thorough clinical, biological, and radiological surveillance.

摘要

引言

拉克氏裂囊肿卒中极为罕见,尤其在婴儿中。最常见的临床表现包括头痛、视野缺损和内分泌功能障碍。治疗选择范围从手术到保守方法,需考虑利弊平衡,特别是在儿童等关键生命阶段。

病例介绍

我们报告一例12岁男孩,因近期出现头痛和尿崩症入院。磁共振成像显示拉克氏裂囊肿卒中。鉴于该青春期早期儿童无压迫症状且基础内分泌检查无异常,采取了保守策略,包括定期进行临床、生物学和放射学随访。该儿童青春期正常,除部分生长激素缺乏外无任何内分泌缺陷。

结论

对于诊断为拉克氏裂囊肿卒中的临床无症状儿童,若有全面的临床、生物学和放射学监测,建议采用保守管理方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/704f/11892514/62574d4cf104/ijem-22-1-143939-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/704f/11892514/e11dc762d626/ijem-22-1-143939-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/704f/11892514/62574d4cf104/ijem-22-1-143939-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/704f/11892514/e11dc762d626/ijem-22-1-143939-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/704f/11892514/62574d4cf104/ijem-22-1-143939-g002.jpg

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Rathke cleft cyst apoplexy: Hormonal and clinical presentation.拉克氏裂囊肿卒中:激素及临床表现
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Rathke's Cleft Cyst Apoplexy in Two Teenage Sisters.两名青少年姐妹的拉克氏裂囊肿卒中
Pediatr Neurosurg. 2019;54(6):428-435. doi: 10.1159/000503112. Epub 2019 Oct 21.
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Outcome of diabetes insipidus in patients with Rathke's cleft cysts.拉克氏裂囊肿患者尿崩症的结局
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Management of endocrine disease: pituitary tumour apoplexy.内分泌疾病的管理:垂体瘤卒中
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A Rathke's Cleft Cyst Presenting with Apoplexy.表现为卒中的拉克氏裂囊肿
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Neurosurg Focus. 2011 Jul;31(1):E2. doi: 10.3171/2011.5.FOCUS1175.
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