• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

复发性隆突性皮肤纤维肉瘤病例——因素与陷阱

Case of recurrent Dermatofibrosarcoma Protuberans- factors and pitfalls.

作者信息

Dewan Ashish Gopal, Sharma Raman, Soni Sanjay, Singh Ishwar, Meher Ravi, Khurana Nita, Sajeed Sameer, Singh Divya, Dewan Aakrith D

机构信息

Department of ENT and Head-Neck Surgery, Maulana Azad Medical College, New Delhi, India.

Department of Pathology, Maulana Azad medical college, New Delhi, India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2025 Jan;77(1):482-486. doi: 10.1007/s12070-024-05143-3. Epub 2024 Oct 28.

DOI:10.1007/s12070-024-05143-3
PMID:40066381
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11890449/
Abstract

Dermatofibrosarcoma protuberans (DFSP) is a benign but locally aggressive tumor originating from the skin's fibroblasts. In its appearance, the tumor can resemble other harmless conditions such as a hypertrophic scar or even acne, with no definitive symptoms. A 32-year-old woman presented with a 2-month history of a lesion over the neck. The histopathology revealed DFSP, and the patient underwent surgical excision with negative margins. However, the lesion recurred after five months, necessitating a revision surgery with adjuvant radiotherapy. We aim to discuss the potential factors contributing to the recurrence. These tumors are best managed in multidisciplinary clinics, and there is a need for long-term surveillance of these patients.

摘要

隆突性皮肤纤维肉瘤(DFSP)是一种起源于皮肤成纤维细胞的良性但具有局部侵袭性的肿瘤。从外观上看,该肿瘤可能类似于其他无害病症,如增生性瘢痕甚至痤疮,没有明确的症状。一名32岁女性颈部出现一个病变,病史2个月。组织病理学检查显示为DFSP,患者接受了手术切除,切缘阴性。然而,病变在五个月后复发,需要进行翻修手术并辅助放疗。我们旨在讨论导致复发的潜在因素。这些肿瘤最好在多学科诊所进行管理,并且需要对这些患者进行长期监测。

相似文献

1
Case of recurrent Dermatofibrosarcoma Protuberans- factors and pitfalls.复发性隆突性皮肤纤维肉瘤病例——因素与陷阱
Indian J Otolaryngol Head Neck Surg. 2025 Jan;77(1):482-486. doi: 10.1007/s12070-024-05143-3. Epub 2024 Oct 28.
2
The efficacy of adjuvant radiotherapy in dermatofibrosarcoma protuberans: a systemic review and meta-analysis.辅助放疗在隆突性皮肤纤维肉瘤中的疗效:系统评价和荟萃分析。
J Eur Acad Dermatol Venereol. 2016 Jul;30(7):1107-14. doi: 10.1111/jdv.13601. Epub 2016 Feb 16.
3
Dermatofibrosarcoma protuberans of the scalp: Surgical management in a multicentric series of 11 cases and systematic review of the literature.头皮隆突性皮肤纤维肉瘤:11 例多中心系列手术治疗及文献系统回顾
Surgery. 2023 Jun;173(6):1463-1475. doi: 10.1016/j.surg.2023.02.026. Epub 2023 Apr 1.
4
Impact of Dermatology Access on Dermatofibrosarcoma Protuberans Outcomes: A Retrospective Study in a Larger Cohort.皮肤科诊疗可及性对隆突性皮肤纤维肉瘤预后的影响:一项更大队列的回顾性研究
S D Med. 2025 May;78(suppl 5):s30.
5
Laser therapy for treating hypertrophic and keloid scars.激光疗法治疗增生性瘢痕和瘢痕疙瘩。
Cochrane Database Syst Rev. 2022 Sep 26;9(9):CD011642. doi: 10.1002/14651858.CD011642.pub2.
6
St Andrews Referral Delay in Skin Cancer (StARDISC): a study of keratinocyte skin cancer time to treatment, growth, invasiveness, British Association of Dermatologists risk factors and excision adequacy.圣安德鲁斯皮肤癌转诊延迟研究(StARDISC):一项关于角质形成细胞皮肤癌治疗时间、生长、侵袭性、英国皮肤科医师协会危险因素及切除充分性的研究。
Br J Dermatol. 2025 Jun 20;193(1):157-166. doi: 10.1093/bjd/ljaf097.
7
What Are the Recurrence Rates, Complications, and Functional Outcomes After Multiportal Arthroscopic Synovectomy for Patients With Knee Diffuse-type Tenosynovial Giant-cell Tumors?膝关节弥漫型腱鞘巨细胞瘤患者行多入路关节镜下滑膜切除术的复发率、并发症及功能结局如何?
Clin Orthop Relat Res. 2024 Jul 1;482(7):1218-1229. doi: 10.1097/CORR.0000000000002934. Epub 2023 Dec 28.
8
Treatment Outcomes and Patterns of Disease Recurrence of Patients with Carcinoma of the Buccal Mucosa.颊黏膜癌患者的治疗结果与疾病复发模式
Indian J Otolaryngol Head Neck Surg. 2024 Dec;76(6):5209-5220. doi: 10.1007/s12070-024-04948-6. Epub 2024 Aug 30.
9
Does Augmenting Irradiated Autografts With Free Vascularized Fibula Graft in Patients With Bone Loss From a Malignant Tumor Achieve Union, Function, and Complication Rate Comparably to Patients Without Bone Loss and Augmentation When Reconstructing Intercalary Resections in the Lower Extremity?对于因恶性肿瘤导致骨缺损的患者,在重建下肢节段性切除时,采用带血管游离腓骨移植来增强照射后的自体骨移植,其骨愈合、功能及并发症发生率与无骨缺损且未进行增强的患者相比是否相当?
Clin Orthop Relat Res. 2025 Jun 26. doi: 10.1097/CORR.0000000000003599.
10
Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment.口腔和口咽癌的治疗干预措施:手术治疗。
Cochrane Database Syst Rev. 2023 Aug 31;8(8):CD006205. doi: 10.1002/14651858.CD006205.pub5.

本文引用的文献

1
Wide Local Excision for Dermatofibrosarcoma Protuberans: A Single-Center Series of 90 Patients.隆突性皮肤纤维肉瘤的广泛局部切除:单中心90例患者系列研究
Biomed Res Int. 2015;2015:642549. doi: 10.1155/2015/642549. Epub 2015 Nov 25.
2
Mohs micrographic surgery in dermatofibrosarcoma protuberans allows tumour clearance with smaller margins and greater preservation of healthy tissue compared with conventional surgery: a study of 74 primary cases.Mohs 显微外科手术在隆突性皮肤纤维肉瘤中的应用可在与传统手术相比切除肿瘤时,保留更小的边缘和更多的健康组织:74 例原发性病例研究。
Br J Dermatol. 2015;172(5):1303-7. doi: 10.1111/bjd.13417. Epub 2015 Mar 9.
3
Mohs micrographic surgery for dermatofibrosarcoma protuberans (DFSP): a single-centre series of 76 patients treated by frozen-section Mohs micrographic surgery with a review of the literature.Mohs 显微外科手术治疗隆突性皮肤纤维肉瘤(DFSP):单中心 76 例冷冻切片 Mohs 显微外科手术治疗的系列研究及文献复习。
J Plast Reconstr Aesthet Surg. 2014 Oct;67(10):1315-21. doi: 10.1016/j.bjps.2014.05.021. Epub 2014 May 23.
4
Dermatofibrosarcoma protuberans with fibrosarcomatous transformation of the head and neck.头颈部隆突性皮肤纤维肉瘤伴纤维肉瘤变
Head Neck Oncol. 2011 Feb 4;3:5. doi: 10.1186/1758-3284-3-5.
5
Dermatofibrosarcoma protuberans (DFSP): predictors of recurrence and the use of systemic therapy.隆突性皮肤纤维肉瘤(DFSP):复发的预测因素和系统治疗的应用。
Ann Surg Oncol. 2011 Feb;18(2):328-36. doi: 10.1245/s10434-010-1316-5. Epub 2010 Sep 16.
6
Molecular targeting of dermatofibrosarcoma protuberans: a new approach to a surgical disease.隆突性皮肤纤维肉瘤的分子靶向治疗:一种针对外科疾病的新方法。
J Natl Compr Canc Netw. 2007 May;5(5):557-62. doi: 10.6004/jnccn.2007.0049.
7
Dermatofibrosarcoma protuberans of the head and neck.头颈部隆突性皮肤纤维肉瘤
Ann Surg Oncol. 2000 Oct;7(9):696-704. doi: 10.1007/s10434-000-0696-3.
8
Dermatofibrosarcoma protuberans of the head and neck. A report of 16 cases.
Arch Otolaryngol Head Neck Surg. 1993 Aug;119(8):891-6. doi: 10.1001/archotol.1993.01880200097014.
9
Dermatofibrosarcoma protuberans of the head and neck.
Arch Otolaryngol. 1984 Jun;110(6):398-404. doi: 10.1001/archotol.1984.00800320052012.
10
Dermatofibrosarcoma protuberans. A clinico-pathological study of nineteen cases and review of world literature.隆突性皮肤纤维肉瘤。19例临床病理研究并复习世界文献。
Scand J Plast Reconstr Surg. 1983;17(3):247-52. doi: 10.3109/02844318309013125.