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本文引用的文献

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2
Ocular complaints and diagnoses in spaceflight.太空飞行中的眼部不适与诊断
NPJ Microgravity. 2024 Jan 2;10(1):1. doi: 10.1038/s41526-023-00335-7.
3
Cheers not tears: champagne corks and eye injury.欢呼而非泪水:香槟瓶塞与眼外伤
BMJ. 2023 Dec 20;383:2520. doi: 10.1136/bmj.p2520.
4
Dry eye disease in astronauts: a narrative review.宇航员的干眼病:一项叙述性综述。
Front Physiol. 2023 Oct 19;14:1281327. doi: 10.3389/fphys.2023.1281327. eCollection 2023.
5
Artificial Intelligence Frameworks to Detect and Investigate the Pathophysiology of Spaceflight Associated Neuro-Ocular Syndrome (SANS).用于检测和研究航天相关神经-眼综合征(SANS)病理生理学的人工智能框架。
Brain Sci. 2023 Jul 30;13(8):1148. doi: 10.3390/brainsci13081148.
6
The Case for Expanding Visual Assessments During Spaceflight.在太空飞行中扩大视觉评估的案例。
Prehosp Disaster Med. 2023 Aug;38(4):518-521. doi: 10.1017/S1049023X23005964. Epub 2023 Jun 27.
7
Ocular conditions and injuries, detection and management in spaceflight.航天飞行中的眼部疾病与损伤、检测与管理
NPJ Microgravity. 2023 May 16;9(1):37. doi: 10.1038/s41526-023-00279-y.
8
Optic neuropathy in spaceflight-associated neuro-ocular syndrome (SANS).太空飞行相关神经眼科综合征(SANS)中的视神经病变
Ir J Med Sci. 2023 Dec;192(6):3143-3145. doi: 10.1007/s11845-023-03353-2. Epub 2023 Apr 1.
9
Tissue Adhesives for the Management of Corneal Perforations and Challenging Corneal Conditions.用于治疗角膜穿孔和疑难角膜疾病的组织粘合剂。
Clin Ophthalmol. 2023 Jan 15;17:209-223. doi: 10.2147/OPTH.S394454. eCollection 2023.
10
Eugenol protects against Aspergillus fumigatus keratitis by inhibiting inflammatory response and reducing fungal load.丁香酚通过抑制炎症反应和降低真菌负荷来预防烟曲霉角膜炎。
Eur J Pharmacol. 2022 Jun 5;924:174955. doi: 10.1016/j.ejphar.2022.174955. Epub 2022 Apr 15.

航天飞行中角膜损伤的管理及行星任务建议

Management of corneal injuries in spaceflight and recommendations for planetary missions.

作者信息

Suh Alex, Ong Joshua, Waisberg Ethan, Berdahl John, Lee Andrew G

机构信息

Tulane University School of Medicine, New Orleans, Louisiana, USA.

Department of Ophthalmology and Visual Sciences, University of Michigan Kellogg Eye Center, Ann Arbor, Michigan, USA.

出版信息

NPJ Microgravity. 2025 Mar 11;11(1):8. doi: 10.1038/s41526-025-00462-3.

DOI:10.1038/s41526-025-00462-3
PMID:40069185
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11897398/
Abstract

In February 1968, NASA purchased 400 antigravity ballpoint pens from the Fisher Pen Company for the Apollo Program to prevent potential harm to astronauts and equipment. Mechanical pencils previously used in microgravity posed risks like eye injuries from floating fragments penetrating the cornea. The cornea is vulnerable to abrasions, perforations, and chemical burns in such environments, affecting crewmembers aboard the International Space Station (ISS). While they undergo extensive training for emergency situations, there are inherent complexities when faced with eye injuries. In this challenging context, adapting available medications and leveraging emergency medical training is critical for addressing ocular injuries in a high-stakes environment. This paper explores ISS medications and management strategies for corneal injuries, highlighting the need to include effective medications and countermeasures in future ISS medical kits.

摘要

1968年2月,美国国家航空航天局(NASA)为阿波罗计划从费希尔笔业公司购买了400支抗重力圆珠笔,以防止对宇航员和设备造成潜在危害。此前在微重力环境中使用的机械铅笔存在风险,比如漂浮的碎片穿透角膜导致眼部受伤。在这种环境下,角膜容易受到擦伤、穿孔和化学灼伤,影响国际空间站(ISS)上的机组人员。虽然他们接受了针对紧急情况的广泛培训,但面对眼部受伤时仍存在固有的复杂性。在这种具有挑战性的背景下,调整现有药物并利用紧急医疗培训对于在高风险环境中处理眼部损伤至关重要。本文探讨了国际空间站上治疗角膜损伤的药物和管理策略,强调了在未来国际空间站医疗包中纳入有效药物和应对措施的必要性。