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Using KeGFR for Vancomycin Dosing When Renal Clearance Is Acutely Changing: A Simulation Study in a Retrospective Cohort.

作者信息

Bairy Manohar, Khoo Benjamin, Tan Sock Hoon, Peh Leticia Xyn Yen, Lim Siow Yu, Chuang Shen Hui

机构信息

Department of Renal Medicine, Tan Tock Seng Hospital, Singapore.

出版信息

Kidney Med. 2025 Jan 31;7(4):100970. doi: 10.1016/j.xkme.2025.100970. eCollection 2025 Apr.

DOI:10.1016/j.xkme.2025.100970
PMID:40070516
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11893294/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f832/11893294/25b25a4e76e6/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f832/11893294/25b25a4e76e6/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f832/11893294/25b25a4e76e6/gr1.jpg

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本文引用的文献

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Using kinetic eGFR to identify acute kidney injury risk in children undergoing cardiac transplantation.使用动态估算肾小球滤过率（eGFR）识别接受心脏移植的儿童的急性肾损伤风险。
Pediatr Res. 2021 Sep;90(3):632-636. doi: 10.1038/s41390-020-01307-3. Epub 2021 Jan 14.
2
Kinetic GFR Outperforms CKD-EPI for Slow Graft Function Prediction in the Immediate Postoperative Period Following Kidney Transplantation.在肾移植术后即刻，动态肾小球滤过率（Kinetic GFR）在预测移植肾功能延迟恢复方面优于慢性肾脏病流行病学协作组（CKD-EPI）公式。
J Clin Med. 2020 Dec 10;9(12):4003. doi: 10.3390/jcm9124003.
3
Modeling Kinetic Glomerular Filtration Rate in Adults with Stable and Unstable Kidney Function: Vancomycin as the Motivating Example.
成人稳定和不稳定肾功能的肾小球滤过率动力学建模：以万古霉素为例。
Pharmacotherapy. 2020 Sep;40(9):872-879. doi: 10.1002/phar.2442. Epub 2020 Aug 4.
4
Using Kinetic eGFR for Drug Dosing in AKI: Concordance between Kinetic eGFR, Cockroft-Gault Estimated Creatinine Clearance, and MDRD eGFR for Drug Dosing Categories in a Pilot Study Cohort.利用动力学 eGFR 进行 AKI 中的药物剂量调整：在一项试点研究队列中，动力学 eGFR、 Cockroft-Gault 估算的肌酐清除率和 MDRD eGFR 用于药物剂量分类的一致性。
Nephron. 2020;144(6):299-303. doi: 10.1159/000507260. Epub 2020 May 5.
5
The value of kinetic glomerular filtration rate estimation on medication dosing in acute kidney injury.动力学肾小球滤过率估计在急性肾损伤药物剂量调整中的价值。
PLoS One. 2019 Nov 26;14(11):e0225601. doi: 10.1371/journal.pone.0225601. eCollection 2019.
6
Predictability of serum vancomycin concentrations using the kinetic estimated glomerular filtration rate formula for critically ill patients
.使用动力学估计肾小球滤过率公式预测重症患者血清万古霉素浓度
Int J Clin Pharmacol Ther. 2018 Dec;56(12):612-616. doi: 10.5414/CP203266.
7
Vancomycin levels are frequently subtherapeutic in critically ill patients: a prospective observational study.在危重症患者中，万古霉素水平常常低于治疗剂量：一项前瞻性观察性研究。
Acta Anaesthesiol Scand. 2017 Jul;61(6):627-635. doi: 10.1111/aas.12897. Epub 2017 Apr 25.
8
The clinical utility of kinetic glomerular filtration rate.动态肾小球滤过率的临床应用价值。
Clin Kidney J. 2017 Apr;10(2):202-208. doi: 10.1093/ckj/sfw108. Epub 2016 Dec 30.
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Kinetic estimated glomerular filtration rate and acute kidney injury in cardiac surgery patients.心脏手术患者的动态估计肾小球滤过率与急性肾损伤
J Crit Care. 2016 Feb;31(1):249-54. doi: 10.1016/j.jcrc.2015.11.006. Epub 2015 Nov 11.
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Crit Care. 2014 May 15;18(3):R99. doi: 10.1186/cc13874.