Gafoor Stefan, Agyeman Walter, Atencah Stanley, Chinnatambi Christopher, Appiah-Pippim James
Graduate Medical Education, Piedmont Athens Regional Hospital, Athens, USA.
Internal Medicine, Piedmont Athens Regional Medical Center, Athens, USA.
Cureus. 2025 Feb 8;17(2):e78753. doi: 10.7759/cureus.78753. eCollection 2025 Feb.
Staphylococcal infection is as common as streptococcal infection as a cause of infection-related glomerulonephritis (IRGN). It is seen more frequently in the pediatric population and is relatively rare in adults. Glomerular disease manifests as either nephritic or nephrotic syndrome. A high index of suspicion is necessary for diagnosing this condition as it can be mistaken for other common conditions in the elderly. IRGN may present as volume overload and may masquerade as cardiorenal syndrome type 1 in patients with preexisting heart failure, emphasizing the importance of distinguishing between the two because the treatment and prognosis may be different. We present an older adult male who was evaluated for suspected acute decompensation of heart failure in the setting of recent left knee septic arthritis and was found to have IRGN. This diagnosis may be delayed or missed due to it mimicking similar conditions and it requires a high index of suspicion.
作为感染相关性肾小球肾炎（IRGN）的病因，葡萄球菌感染与链球菌感染同样常见。它在儿科人群中更为常见，在成人中相对少见。肾小球疾病表现为肾炎综合征或肾病综合征。由于在老年人中它可能被误诊为其他常见疾病，因此诊断这种疾病需要高度的怀疑指数。IRGN可能表现为容量超负荷，在已有心力衰竭的患者中可能伪装成1型心肾综合征，这凸显了区分两者的重要性，因为治疗和预后可能不同。我们报告一名老年男性，他因近期左膝化脓性关节炎被评估为疑似心力衰竭急性失代偿，结果发现患有IRGN。由于它会模仿类似病症，该诊断可能会延迟或漏诊，这需要高度的怀疑指数。
