Shao Sai, Wang Guangbin
Department of Radiology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.
Front Neurol. 2025 Feb 25;16:1536581. doi: 10.3389/fneur.2025.1536581. eCollection 2025.
Extracranial cervical artery dissection (eCAD) is the second leading cause of stroke in young and middle-aged adults. Clinical management strategies for eCAD are continuously being explored and optimized, as revealed by the recently published CADISS and TREAT-CAD studies. The type of drug, dosage, and timing of administration can affect the regression of carotid artery dissection and the risk of recurrence of stroke. Based on imaging evidence, it is important to develop individualized treatment strategies for different risk groups. Currently, High-resolution magnetic resonance vessel wall imaging (MR-VWI) technology has made significant progress in the qualitative diagnosis of eCAD, vascular lesion progression, and the assessment of recurring ischemic stroke risk. To better understand the pathogenesis and progression of eCAD using MR-VWI, a comprehensive review is presented here.
颅外颈动脉夹层(eCAD)是中青年人群中第二大常见的中风病因。正如最近发表的CADISS和TREAT-CAD研究所显示的那样,eCAD的临床管理策略正在不断探索和优化。药物类型、剂量和给药时机可影响颈动脉夹层的消退以及中风复发风险。基于影像学证据,为不同风险组制定个体化治疗策略很重要。目前,高分辨率磁共振血管壁成像(MR-VWI)技术在eCAD的定性诊断、血管病变进展以及复发性缺血性中风风险评估方面取得了重大进展。为了使用MR-VWI更好地理解eCAD的发病机制和进展,本文进行了全面综述。