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Allogeneic hematopoietic cell transplantation after infection with SARS-CoV-2 during the COVID-19 pandemic: a multicenter retrospective analysis.2019年冠状病毒病大流行期间感染严重急性呼吸综合征冠状病毒2后进行异基因造血细胞移植：一项多中心回顾性分析
Bone Marrow Transplant. 2025 May;60(5):733-736. doi: 10.1038/s41409-025-02548-8. Epub 2025 Mar 12.
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Impact of SARS-CoV-2 pandemic on rehabilitation of patients after high-dose chemotherapy with allogeneic hematopoietic stem cell transplantation: results of a monocentric, retrospective analysis.SARS-CoV-2 大流行对接受大剂量化疗联合异基因造血干细胞移植后患者康复的影响：一项单中心回顾性分析的结果。
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Impact of SARS-CoV-2 in Hematopoietic Stem Cell Transplantation and Chimeric Antigen Receptor T Cell Therapy Recipients.新型冠状病毒对造血干细胞移植和嵌合抗原受体 T 细胞治疗受者的影响。
Transplant Cell Ther. 2021 Sep;27(9):796.e1-796.e7. doi: 10.1016/j.jtct.2021.07.005. Epub 2021 Jul 10.
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Transplant Cell Ther. 2022 Jun;28(6):337.e1-337.e10. doi: 10.1016/j.jtct.2022.03.010. Epub 2022 Mar 13.
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No transmission of SARS-CoV-2 in a patient undergoing allogeneic hematopoietic cell transplantation from a matched-related donor with unknown COVID-19.在接受来自匹配相关供体的异基因造血细胞移植且供体新冠病毒病情况未知的患者中，未发生严重急性呼吸综合征冠状病毒2（SARS-CoV-2）传播。
Transfus Apher Sci. 2020 Dec;59(6):102921. doi: 10.1016/j.transci.2020.102921. Epub 2020 Aug 24.
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Case Report: Favorable outcome of allogeneic hematopoietic stem cell transplantation in SARSCoV2 positive recipient, risk-benefit balance between infection and leukemia.病例报告：SARS-CoV-2 阳性受者异基因造血干细胞移植的良好结局，感染与白血病之间的风险效益平衡。
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Clin Infect Dis. 2024 Aug 16;79(2):542-554. doi: 10.1093/cid/ciae291.
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Recent infection with SARS-CoV-2 in donors was associated with a higher incidence of acute graft-versus-host disease in recipients undergoing allogeneic haematopoietic stem cell transplantation.供者近期感染 SARS-CoV-2 与接受异基因造血干细胞移植的受者发生急性移植物抗宿主病的发生率较高有关。
Br J Haematol. 2024 Aug;205(2):452-462. doi: 10.1111/bjh.19594. Epub 2024 Jun 24.
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Immunogenicity and Safety of Booster SARS-CoV-2 mRNA Vaccine Dose in Allogeneic Hematopoietic Stem Cell Transplantation Recipients.异基因造血干细胞移植受者加强型 SARS-CoV-2 mRNA 疫苗接种的免疫原性和安全性。
Transplant Cell Ther. 2023 Nov;29(11):706.e1-706.e7. doi: 10.1016/j.jtct.2023.08.008. Epub 2023 Aug 13.

本文引用的文献

1
Outcome of COVID-19 in allogeneic stem cell transplant recipients: Results from the EPICOVIDEHA registry.异基因造血干细胞移植受者 COVID-19 结局：EPICOVIDEHA 登记研究结果。
Front Immunol. 2023 Feb 24;14:1125030. doi: 10.3389/fimmu.2023.1125030. eCollection 2023.
2
Allogeneic stem cell transplantation in acute leukemia patients after COVID-19 infection.新型冠状病毒肺炎感染后急性白血病患者的异基因干细胞移植
Bone Marrow Transplant. 2021 Jun;56(6):1478-1481. doi: 10.1038/s41409-021-01225-w. Epub 2021 Feb 9.
3
COVID-19 in immunocompromised patients: A systematic review of cancer, hematopoietic cell and solid organ transplant patients.免疫功能低下患者中的 COVID-19：癌症、造血细胞和实体器官移植患者的系统评价。
J Infect. 2021 Mar;82(3):329-338. doi: 10.1016/j.jinf.2021.01.022. Epub 2021 Feb 4.
4
Longitudinal analyses reveal immunological misfiring in severe COVID-19.纵向分析揭示了重症 COVID-19 中的免疫失调。
Nature. 2020 Aug;584(7821):463-469. doi: 10.1038/s41586-020-2588-y. Epub 2020 Jul 27.
5
The challenge of COVID-19 and hematopoietic cell transplantation; EBMT recommendations for management of hematopoietic cell transplant recipients, their donors, and patients undergoing CAR T-cell therapy.COVID-19 和造血细胞移植面临的挑战；EBMT 关于造血细胞移植受者、供者和接受 CAR-T 细胞治疗患者管理的建议。
Bone Marrow Transplant. 2020 Nov;55(11):2071-2076. doi: 10.1038/s41409-020-0919-0. Epub 2020 May 13.
6
Who is fit for allogeneic transplantation?谁适合异体移植？
Blood. 2010 Dec 2;116(23):4762-70. doi: 10.1182/blood-2010-07-259358. Epub 2010 Aug 11.
7
Immunobiology of allogeneic hematopoietic stem cell transplantation.异基因造血干细胞移植的免疫生物学
Annu Rev Immunol. 2007;25:139-70. doi: 10.1146/annurev.immunol.25.022106.141606.

Allogeneic hematopoietic cell transplantation after infection with SARS-CoV-2 during the COVID-19 pandemic: a multicenter retrospective analysis.

作者信息

Ahmad Osama, Kröger Nicolaus, Wagner-Drouet Eva, Nachbaur David, Steiner Normann, Teschner Daniel, Kraus Sabrina, Bug Gesine, Ajib Salem, Schetelig Johannes, Bethge Wolfgang Andreas, Schroeder Thomas, Schaffrath Judith, Müller Lutz Peter, Verbeek Mareike, Jost Edgar, Soysal Hatice, Tischer Johanna, Franke Georg-Nikolaus, Klein Stefan, Holtick Udo, Wendelin Knut, Lengerke Claudia, Bornhäuser Martin, Weller Jan Frederic, Christopeit Maximilian

机构信息

Department of Hematology, Oncology, Clinical Immunology and Rheumatology, University Hospital Tuebingen, Tuebingen, Germany.

University Medical Center Hamburg, Hamburg, Germany.

出版信息

Bone Marrow Transplant. 2025 May;60(5):733-736. doi: 10.1038/s41409-025-02548-8. Epub 2025 Mar 12.

DOI:
10.1038/s41409-025-02548-8
PMID:40074786
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12061770/
Abstract
摘要