Kristiansen Katrine Vestergaard, Schrøder Anders Simon, Bienzle Dorothee, Vedel Tanja, Agerholm Jørgen Steen, Berendt Mette
Department of Veterinary Clinical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Dyrlaegevej 16, Frederiksberg C, DK-1870, Denmark.
Department of Pathobiology, Ontario Veterinary College, University of Guelph, 50 Stone Road East, Guelph, Ontario, N1G 2W1, Canada.
Acta Vet Scand. 2025 Mar 12;67(1):12. doi: 10.1186/s13028-025-00800-1.
Spinal neoplasms are sparsely documented in juvenile dogs. Case reports and small case series have described nephroblastomas, primitive neuroectodermal tumours, gliomas, certain sarcomas, and osteochondromas, but round cell sarcomas have not previously been documented.
This case report describes a 10-week-old female Rottweiler puppy with acute onset of progressive ataxia and pelvic limb lameness. Neurological examination localised a T3-L3 myelopathy and MRI revealed an ovoid, well-marginated mass extending from mid L3 to caudal L4 vertebrae. Post-mortem examination, histopathology, and immunohistochemistry confirmed a round cell sarcoma of extradural origin.
Our case report stresses the importance of performing MRI even in very young individuals with acute progressive signs of spinal cord lesions. Clinicians should include spinal tumours as a differential diagnosis for juvenile canines with spinal neurological signs. Round cell sarcoma should be added to the list of spinal tumours in young dogs.
幼年犬脊柱肿瘤的相关记录较少。病例报告和小病例系列描述了肾母细胞瘤、原始神经外胚层肿瘤、胶质瘤、某些肉瘤和骨软骨瘤,但此前尚未有圆形细胞肉瘤的记录。
本病例报告描述了一只10周龄雌性罗威纳幼犬,急性起病,出现进行性共济失调和后肢跛行。神经系统检查定位为T3-L3脊髓病,MRI显示一个椭圆形、边界清晰的肿块,从L3中部延伸至L4椎体尾部。尸检、组织病理学和免疫组织化学证实为硬膜外起源的圆形细胞肉瘤。
我们的病例报告强调,即使是非常年幼且有急性进行性脊髓损伤体征的个体,进行MRI检查也很重要。临床医生应将脊柱肿瘤作为有脊柱神经体征的幼年犬的鉴别诊断之一。圆形细胞肉瘤应添加到幼犬脊柱肿瘤列表中。