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关节镜与抗生素浸渍珠联合治疗化脓性肩关节炎的疗效:病例系列

Effectiveness of a combined arthroscopic and antibiotic-impregnated bead approach for septic shoulder arthritis management: a case series.

作者信息

Park Sung-Jin, Park Sam-Guk

机构信息

Department of Orthopedic Surgery, Yeungnam University College of Medicine, Daegu, Korea.

出版信息

Clin Shoulder Elb. 2025 Mar;28(1):31-39. doi: 10.5397/cise.2024.00584. Epub 2025 Feb 17.

Abstract

BACKGROUND

This study sought to evaluate the effectiveness of a combined treatment approach for septic shoulder arthritis involving arthroscopic synovectomy and use of antibiotic-impregnated polymethylmethacrylate (PMMA) beads for localized antibiotic delivery.

METHODS

This retrospective study included 22 patients with septic shoulder arthritis treated at our institution between 2017 and 2023. The treatment involved arthroscopic lavage, debridement, and insertion of antibiotic-impregnated PMMA beads. Patients were evaluated preoperatively and postoperatively based on laboratory tests, imaging, joint fluid analysis, and physical examination. Treatment efficacy was assessed based on normalization of C-reactive protein (CRP) levels, pain reduction as measured using a visual analog scale (VAS), and improvement in shoulder function according to Constant-Murley score.

RESULTS

All 22 patients demonstrated successful resolution of infection, with only one case of recurrence, leading to a notably low recurrence rate of 5%. Recurrence was determined based on clinical signs (aggravated pain, swelling, and fever) and laboratory markers (elevated CRP and white blood cell count). Mean follow-up duration was 20.2 months. Significant reductions in pain (average VAS score reduction from 8.1 to 2.4, P<0.001) were observed, and mean Constant-Murley score at final follow-up was 60.7, reflecting improved shoulder function.

CONCLUSIONS

Arthroscopic debridement combined with localized antibiotic delivery using PMMA beads is an effective and safe treatment for septic shoulder arthritis. This method offers substantial advantages over traditional treatments, as evidenced by the very low recurrence rate. Level of evidence: IV.

摘要

背景

本研究旨在评估一种联合治疗方法对化脓性肩关节关节炎的有效性,该方法包括关节镜下滑膜切除术以及使用含抗生素的聚甲基丙烯酸甲酯(PMMA)珠粒进行局部抗生素递送。

方法

这项回顾性研究纳入了2017年至2023年间在本机构接受治疗的22例化脓性肩关节关节炎患者。治疗包括关节镜冲洗、清创以及插入含抗生素的PMMA珠粒。根据实验室检查、影像学、关节液分析和体格检查对患者进行术前和术后评估。基于C反应蛋白(CRP)水平正常化、使用视觉模拟量表(VAS)测量的疼痛减轻以及根据Constant-Murley评分评估的肩部功能改善来评估治疗效果。

结果

所有22例患者感染均成功得到解决,仅1例复发,复发率低至5%。根据临床体征(疼痛加剧、肿胀和发热)和实验室指标(CRP和白细胞计数升高)确定复发情况。平均随访时间为20.2个月。观察到疼痛显著减轻(平均VAS评分从8.1降至2.4,P<0.001),末次随访时平均Constant-Murley评分为60.7,表明肩部功能有所改善。

结论

关节镜清创联合使用PMMA珠粒进行局部抗生素递送是治疗化脓性肩关节关节炎的一种有效且安全的方法。与传统治疗方法相比,该方法具有显著优势,复发率极低即证明了这一点。证据级别:IV。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98e0/11938927/119fcfc659f9/cise-2024-00584f1.jpg

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