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三种不同麻醉方案下小儿硬质支气管镜检查并发症的调查

An Investigation of the Pediatric Rigid Bronchoscopy Complication with Three Different Anesthesia Regimes.

作者信息

Chavoshi Tahereh, Rokhtabnak Faranak, Nouri Nasrin, Mojaveraghili Seyedbabak, Eshghi Alireza, Salehi Reza

机构信息

Department of Anesthesiology, Aliasghar Children's Hospital, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.

Department of Anesthesiology, Firoozgar Hospital, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.

出版信息

Anesth Pain Med. 2024 Sep 28;14(4):e150953. doi: 10.5812/aapm-150953. eCollection 2024 Aug.

Abstract

BACKGROUND

Foreign body aspiration is common in children and poses a significant risk of morbidity and mortality. Rigid bronchoscopy is the most common method for removing aspirated foreign bodies.

OBJECTIVES

Anesthesiologists play a critical role in managing these procedures, aiming to find the best strategies with the fewest complications. This study aims to compare anesthesia-related complications during rigid bronchoscopy in children using muscle relaxants versus no muscle relaxants.

METHODS

In this clinical trial, 60 eligible children were randomly divided into three equal groups: SP: Spontaneous ventilation with sevoflurane and propofol; VA: Controlled ventilation with sevoflurane and atracurium; VR: Controlled ventilation with sevoflurane and rocuronium. At the end of anesthesia, complications such as cough, bucking, hypoxemia, laryngospasm, and bronchospasm were compared, along with the pulmonologist's level of satisfaction, surgery duration, and total anesthesia time in the three groups.

RESULTS

The comparison between the SP, VR, and VA groups revealed the following: No significant difference was found in the incidence of cough and respiratory distress following foreign body aspiration among the three groups (P = 0.262 and P = 0.762, respectively); minimum oxygen saturation during rigid bronchoscopy differed significantly between the groups (P = 0.013); bucking during bronchoscopy was significantly more frequent in the SP group (P = 0.017); laryngospasm was significantly more common in the SP group compared to the other two groups (P = 0.004); agitation during recovery was significantly lower in the propofol (SP) group; pulmonologist satisfaction was highest in the VR group, followed by the VA group, with a significant difference compared to the SP group (P = 0.021); although the SP group experienced more frequent hypoxemia, the difference was not statistically significant; there was no significant difference in anesthesia or bronchoscopy duration across the three groups.

CONCLUSIONS

The study results suggest that using muscle relaxants in rigid bronchoscopy offers several advantages, including fewer intraoperative complications such as bucking and laryngospasm. Additionally, controlled ventilation reduced the need for intravenous anesthetics and opioids, minimizing adverse effects and shortening recovery times.

摘要

背景

异物吸入在儿童中很常见,会带来显著的发病和死亡风险。硬质支气管镜检查是取出吸入异物最常用的方法。

目的

麻醉医生在管理这些手术中起着关键作用,旨在找到并发症最少的最佳策略。本研究旨在比较在儿童硬质支气管镜检查中使用肌肉松弛剂与不使用肌肉松弛剂时与麻醉相关的并发症。

方法

在这项临床试验中,60名符合条件的儿童被随机分为三组,每组人数相等:SP组:七氟醚和丙泊酚维持自主通气;VA组:七氟醚和阿曲库铵控制通气;VR组:七氟醚和罗库溴铵控制通气。在麻醉结束时,比较三组咳嗽、呛咳、低氧血症、喉痉挛和支气管痉挛等并发症,以及肺科医生的满意度、手术持续时间和总麻醉时间。

结果

SP组、VR组和VA组之间的比较结果如下:三组异物吸入后咳嗽和呼吸窘迫的发生率无显著差异(分别为P = 0.262和P = 0.762);硬质支气管镜检查期间的最低氧饱和度在各组之间存在显著差异(P = 0.013);支气管镜检查期间呛咳在SP组中明显更频繁(P = 0.017);与其他两组相比,SP组喉痉挛明显更常见(P = 0.004);丙泊酚(SP)组苏醒期躁动明显更低;肺科医生满意度在VR组最高,其次是VA组,与SP组相比有显著差异(P = 0.021);虽然SP组低氧血症更频繁,但差异无统计学意义;三组麻醉或支气管镜检查持续时间无显著差异。

结论

研究结果表明,在硬质支气管镜检查中使用肌肉松弛剂有几个优点,包括减少术中呛咳和喉痉挛等并发症。此外,控制通气减少了静脉麻醉药和阿片类药物的使用,将不良反应降至最低并缩短了恢复时间。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9850/11895795/0185c85e7c5a/aapm-14-4-150953-i001.jpg

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