Stoleru Gianna, Jain Meera, Jones Anna Vi, Podboy Alexander
Division of Gastroenterology and Hepatology, University of Virginia Medical Center, Charlottesville, VA.
Department of Internal Medicine, University of Virginia Medical Center, Charlottesville, VA.
ACG Case Rep J. 2025 Mar 12;12(3):e01644. doi: 10.14309/crj.0000000000001644. eCollection 2025 Mar.
Iron is the most common nutritional deficiency encountered in the United States, with over 15% of Americans using some form of daily oral iron supplementation. Although commonly associated with minor gastrointestinal side effects, severe gastrointestinal complications are rare. Direct cytotoxic mucosal damage and subsequent ulcer formation have rarely been reported. Among reported cases, most are found in the stomach with extragastric manifestations of siderosis being less commonly described. We report a rare case of esophageal siderosis related to oral iron supplementation.
