Omenn G S
Arthritis Rheum. 1977 Mar;20(2 Suppl):484-96.
Because of the tremendous impact of recent findings of association between genes in the major histocompatibility system and certain rheumatic diseases, the genetics of this system and the methods of analyzing disease association are discussed in detail. These associations represent an important step forward in the search for basic causes and mechanisms of these diseases. Further analyses may permit better classification of diseases and increased understanding of the relationships between genetic and environmental factors in the susceptibility to specific disease.
由于近期主要组织相容性系统中的基因与某些风湿性疾病之间关联的研究结果产生了巨大影响，因此将详细讨论该系统的遗传学以及分析疾病关联的方法。这些关联是在探寻这些疾病的根本原因和机制方面向前迈出的重要一步。进一步的分析可能会使疾病分类更加完善，并加深对特定疾病易感性中遗传因素与环境因素之间关系的理解。
