Zelick R, Narins P M
Hear Res. 1985 Feb;17(2):161-76. doi: 10.1016/0378-5955(85)90019-x.
While recording from single auditory nerve fibers in a frog, a monaural 3 min pure tone stimulus at CF was used to induce temporary threshold shift (TTS). TTS magnitude was correlated with the exposure tone intensity relative to the pre-exposure best threshold of the neuron, but not with exposure tone absolute intensity. CF and spontaneous spike rate were also uncorrelated with TTS magnitude. Comparison of frequency-threshold curves (FTCs) made before and successively after exposure revealed either a maximum sensitivity loss at the tip of the FTC or an equal shift at all frequencies. Neurons tended to recover from TTS within 3 min post-exposure, regardless of the initial TTS. Thus, recovery from TTS was more rapid for larger shifts. Recovery dynamics followed single or a double negative exponential functions.
在对青蛙的单根听神经纤维进行记录时，使用了在特征频率（CF）下的单耳3分钟纯音刺激来诱发暂时性阈移（TTS）。TTS的大小与相对于神经元暴露前最佳阈值的暴露音强度相关，而与暴露音的绝对强度无关。特征频率和自发放电率也与TTS大小无关。对暴露前后连续制作的频率-阈值曲线（FTC）进行比较，结果显示FTC顶端的最大敏感度损失，或所有频率处的同等偏移。无论初始TTS如何，神经元在暴露后3分钟内倾向于从TTS中恢复。因此，TTS越大，恢复越快。恢复动态遵循单或双负指数函数。
