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伴有急性气道梗阻的甲状腺危象女性患者的管理:一例报告

Management of a female patient with thyroid storm accompanied by acute airway obstruction: A case report.

作者信息

Wang Lintao, Ming Kunxiu, Yan Zhiyuan, Huang Jinning, Wang Yonghui

机构信息

Department of Clinical Medicine, Weifang People's Hospital, Shandong Second Medical University, Weifang, Shandong 261041, P.R. China.

Department of Central Sterile Supply, Weifang People's Hospital, Weifang, Shandong 261041, P.R. China.

出版信息

Exp Ther Med. 2025 Mar 4;29(4):89. doi: 10.3892/etm.2025.12839. eCollection 2025 Apr.

DOI:10.3892/etm.2025.12839
PMID:40084196
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11904869/
Abstract

Thyroid storm (TS) is a life-threatening exacerbation of the hyperthyroid state. Acute airway obstruction is a life-threatening disease that requires emergency intervention. The present report describes a case of concomitant TS (Burch-Wartofsky Point Scale score, 70 points; thyroid-stimulating hormone, <0.01 µIU/ml; free triiodothyronine, 30.8 pmol/l; and free thyroxine, 106.7 pmol/l) and acute airway obstruction in a 63-year-old female patient. Although treating the TS was viewed as the primary medical concern, the airway obstruction induced by the large thyroid also needed to be solved urgently. In the present case, thyroidectomy was immediately performed, following which the TS was controlled by medical treatment (propylthiouracil, sodium iodide, hydrocortisone and esmolol). After the surgery, the airway obstruction and TS were alleviated, before the patient was eventually discharged from the hospital 14 days after surgery. At 1 month after discharge from the hospital, the patient had normal thyroid function with oral intake of levothyroxine tablet and did not complain of dyspnoea. The present case report aims to emphasize the need for the heightened awareness of patients with TS and trachea stenosis, and underscore the importance of solving the airway obstruction accompanying the TS.

摘要

甲状腺危象(TS)是甲状腺功能亢进状态的一种危及生命的加重情况。急性气道梗阻是一种需要紧急干预的危及生命的疾病。本报告描述了一名63岁女性患者同时发生甲状腺危象(伯奇 - 沃托夫斯基评分量表得分70分;促甲状腺激素<0.01 μIU/ml;游离三碘甲状腺原氨酸30.8 pmol/l;游离甲状腺素106.7 pmol/l)和急性气道梗阻的病例。尽管治疗甲状腺危象被视为主要医疗关注点,但肿大甲状腺引起的气道梗阻也需要紧急解决。在本病例中,立即进行了甲状腺切除术,随后通过药物治疗(丙硫氧嘧啶、碘化钠、氢化可的松和艾司洛尔)控制了甲状腺危象。手术后,气道梗阻和甲状腺危象得到缓解,患者最终在术后14天出院。出院1个月后,患者口服左甲状腺素片,甲状腺功能正常,未诉呼吸困难。本病例报告旨在强调对甲状腺危象和气管狭窄患者提高认识的必要性,并强调解决伴随甲状腺危象的气道梗阻的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d07/11904869/cd077cab6fc2/etm-29-04-12839-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d07/11904869/1bd26f57a188/etm-29-04-12839-g00.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d07/11904869/743391991034/etm-29-04-12839-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d07/11904869/cd077cab6fc2/etm-29-04-12839-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d07/11904869/1bd26f57a188/etm-29-04-12839-g00.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d07/11904869/743391991034/etm-29-04-12839-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d07/11904869/cd077cab6fc2/etm-29-04-12839-g02.jpg

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本文引用的文献

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High risk and low prevalence diseases: Thyroid storm.高危低发疾病:甲状腺危象。
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Hyperthyroidism: aetiology, pathogenesis, diagnosis, management, complications, and prognosis.甲状腺功能亢进症:病因、发病机制、诊断、治疗、并发症和预后。
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