Guyatt G H, Thompson P J, Berman L B, Sullivan M J, Townsend M, Jones N L, Pugsley S O
J Chronic Dis. 1985;38(6):517-24. doi: 10.1016/0021-9681(85)90035-9.
To elucidate the characteristics of measures of function in patients with chronic heart failure and chronic lung disease we administered four functional status questionnaires, a 6-min walk test and a cycle ergometer exercise test, to 43 patients limited in their day to day activities as a result of their underlying heart or lung disease. Correlations between these measures were calculated using Spearman's rank order correlation coefficient. The walk test correlated well with the cycle ergometer (r = 0.579), and almost as well with the four functional status questionnaires (r = 0.473-0.590) as the questionnaires did with one another (0.423-0.729). On the other hand, correlations between cycle ergometer results and the questionnaires was in each case 0.295 or lower, and none of these correlations reached statistical significance. These results suggest that exercise capacity in the laboratory can be differentiated from functional exercise capacity (the ability to undertake physically demanding activities of daily living) and that the walk test provides a good measure of function in patients with heart and lung disease.
为阐明慢性心力衰竭和慢性肺病患者功能测量指标的特征，我们对43例因潜在心肺疾病而日常活动受限的患者进行了四项功能状态问卷、6分钟步行试验和蹬车测力计运动试验。使用Spearman等级相关系数计算这些测量指标之间的相关性。步行试验与蹬车测力计相关性良好（r = 0.579），与四项功能状态问卷的相关性几乎相同（r = 0.473 - 0.590），与问卷之间的相关性（0.423 - 0.729）相当。另一方面，蹬车测力计结果与问卷之间的相关性在每种情况下均为0.295或更低，且这些相关性均未达到统计学显著性。这些结果表明，实验室中的运动能力可与功能性运动能力（进行日常体力要求高的活动的能力）区分开来，且步行试验可为心肺疾病患者的功能提供良好的测量指标。
