Schreyer P, Caspi E, Ariely S, Herzianu I, User P, Gilboa Y, Zaidman J L
Eur J Obstet Gynecol Reprod Biol. 1979 Apr;9(2):97-103. doi: 10.1016/0028-2243(79)90005-4.
The effect of intravenous administration of ritodrine on blood glucose, insulin, free fatty acids and electrolytes in 17 third-trimester gravidas was investigated. A highly significant increase in blood glucose, insulin and free fatty acids and a marked decrease in serum potassium levels were registered. No significant changes during ritodrine infusion were recorded in serum levels of sodium, chloride, calcium, phosphorus and magnesium. No cardiac arrhythmias or electrocardiographic deteriorations occurred. While intravenous ritodrine administration seems to be safe in normal pregnancy, there may be a risk in diabetic patients, digitalized cases and those patients being treated with diuretics.
研究了静脉注射利托君对17例孕晚期孕妇血糖、胰岛素、游离脂肪酸和电解质的影响。结果显示血糖、胰岛素和游离脂肪酸显著升高，血清钾水平明显降低。利托君输注期间，血清钠、氯、钙、磷和镁水平无显著变化。未发生心律失常或心电图恶化。虽然静脉注射利托君在正常妊娠中似乎是安全的，但糖尿病患者、使用洋地黄的患者以及正在接受利尿剂治疗的患者可能存在风险。
