Lin Alex, Varma Dinesh, Mitra Biswadev
School of Public Health & Preventive Medicine, Monash University, Melbourne, VIC, 3004, Australia.
Emergency & Trauma Centre, The Alfred Hospital, Melbourne, Australia.
Emerg Radiol. 2025 Apr;32(2):195-202. doi: 10.1007/s10140-025-02329-2. Epub 2025 Mar 15.
The aim of this study was to quantify the proportion of chest x-rays (CXRs) for non-traumatic chest pain (NTCP) in the emergency department (ED) that were abnormal and assess the clinical significance of these abnormalities. We also aimed to explore the variables associated with abnormal and clinically significant abnormal CXRs, to predict a population where CXRs can be safely avoided.
A single center retrospective cohort study was conducted including all adult patients presenting to a single ED with NTCP between 01 Jan 2022 and 31 Dec 2022. We categorized the CXRs into abnormal, or normal as reported by a radiologist. Abnormalities were categorized to be clinically significant based on potential or actual changes in patient management. The association of patient demographics, presenting vital signs, and clinical characteristics with clinically significant abnormalities were explored using multivariable logistic regression analysis.
There were 3,419 eligible patient encounters included for analysis. Of these, 746 (21.8%; 95%CI: 20.4-23.2%) CXRs had at least one abnormality detected. There were 218 (6.4%; 95%CI: 6.1-7.9%) CXRs deemed to have clinically significant abnormalities. Age categories of 50-64 years (aOR 1.64; 95%CI 1.04-2.60), and age > 64 years (aOR 2.32; 95%CI: 1.51-3.57), history of congestive heart failure (CHF) (aOR 1.86; 95%CI: 1.08-3.21), smoking (aOR 1.27; 95%CI: 1.04-1.57), hemoptysis (aOR 6.69; 95%CI: 1.92-23.33), diminished lung sounds (aOR 4.87; 95%CI:2.95-8.05), rales (aOR 4.49; 95%CI: 2.82-7.15), and abnormal oxygen saturations (aOR 1.98; 95%CI: 1.40-2.79) were associated with clinically significant abnormalities on CXRs. In the absence of these variables, 1.4% (95%CI: 0.6-2.6%) of CXRs were abnormal with clinical significance.
CXRs have a relatively high yield of abnormalities among patients with NTCP. However, some CXRs could be safely avoided in the absence of variables associated with clinically significant abnormalities. Further validation of these clinical characteristics is required before translation to clinical practice.
本研究的目的是量化急诊科(ED)中非创伤性胸痛(NTCP)患者胸部X光片(CXR)异常的比例,并评估这些异常的临床意义。我们还旨在探索与异常及具有临床意义的异常CXR相关的变量,以预测可以安全避免进行CXR检查的人群。
进行了一项单中心回顾性队列研究,纳入了2022年1月1日至2022年12月31日期间因NTCP到单个急诊科就诊的所有成年患者。我们根据放射科医生的报告将CXR分为异常或正常。根据患者管理的潜在或实际变化,将异常分类为具有临床意义。使用多变量逻辑回归分析探索患者人口统计学、呈现的生命体征和临床特征与具有临床意义的异常之间的关联。
共有3419例符合条件的患者就诊纳入分析。其中,746例(21.8%;95%CI:20.4 - 23.2%)CXR至少检测到一项异常。有218例(6.4%;95%CI:6.1 - 7.9%)CXR被认为具有临床意义的异常。年龄在50 - 64岁(调整后比值比[aOR] 1.64;95%CI 1.04 - 2.60)、年龄>64岁(aOR 2.32;95%CI:1.51 - 3.57)、充血性心力衰竭(CHF)病史(aOR 1.86;95%CI:1.08 - 3.21)、吸烟(aOR 1.27;95%CI:1.04 - 1.57)、咯血(aOR 6.69;95%CI:1.92 - 23.33)、肺部听诊减弱(aOR 4.87;95%CI:2.95 - 8.05)、啰音(aOR 4.49;95%CI:2.82 - 7.15)和异常血氧饱和度(aOR 1.98;95%CI:1.40 - 2.79)与CXR上具有临床意义的异常相关。在没有这些变量的情况下,1.4%(95%CI:0.6 - 2.6%)的CXR具有临床意义的异常。
NTCP患者中CXR的异常检出率相对较高。然而,在没有与具有临床意义的异常相关的变量的情况下,一些CXR检查可以安全地避免。在转化为临床实践之前,需要对这些临床特征进行进一步验证。