Liu Xiao-Feng, Zheng Yong-Qiang, Lin Liang, Lin Zhen-Yu, Zhang Hong-Peng, Huang Xiao-Peng, Wang Ze-Feng, Zhang Jin-Shan
Department of Orthopedics, Jinjiang Municipal Hospital (Shanghai Sixth People's Hospital Fujian), Quanzhou, 362000, Fujian, China.
Clinical Research Center for Orthopaedic Trauma and Reconstruction of Fujian Province, Quanzhou, 362000, Fujian, China.
BMC Musculoskelet Disord. 2025 Mar 14;26(1):261. doi: 10.1186/s12891-025-08499-x.
To study the relationship between red blood cell distribution width (RDW) and short-term mortality of hip fracture in middle-aged and older adults.
A retrospective cohort of electronic medical records at a single hospital over a 2-year period between 2020 and 2021. We received the records of 233 patients aged > 50 years who suffered from hip fracture. the clinical data including patients demographics, comorbidities at the time of admission, type of surgery, blood examination, 3-months mortality, 6-months mortality and 1-year mortality. the relationship between RDW and short-term mortality of hip fracture were analyzed. the cohort was then divided into two groups based on their RDW levels at the time of admission: low (RDW < 13.6%) and high (RDW ≥ 13.6%).
Results the mean age was 78.03 ± 12.09 years; 64.81% were woman. At admission, 80 patients (34.33%) had high RDW levels and 153 patients (65.67%) had low RDW levels. there were no statistically significant differences between the groups with regard to sex, type of operation, duration of surgery and hospitalization length. Patients with high RDW had more comorbidities when compared to patients with low RDW levels (p < 0.05). All-cause mortality was higher for patients with high RDW levels, at 3 months (p < 0.05), 6 months (p < 0.05), and 12 months (p < 0.05).
RDW is significantly related with short-term mortality in hip fracture. The higher RDW, the higher risk of mortality.
研究中老年髋部骨折患者红细胞分布宽度（RDW）与短期死亡率之间的关系。
对一家医院2020年至2021年期间2年的电子病历进行回顾性队列研究。我们收集了233例年龄>50岁的髋部骨折患者的记录。临床数据包括患者人口统计学信息、入院时的合并症、手术类型、血液检查、3个月死亡率、6个月死亡率和1年死亡率。分析RDW与髋部骨折短期死亡率之间的关系。然后根据入院时的RDW水平将队列分为两组：低水平（RDW<13.6%）和高水平（RDW≥13.6%）。
平均年龄为78.03±12.09岁；64.81%为女性。入院时，80例患者（34.33%）RDW水平高，153例患者（65.67%）RDW水平低。两组在性别、手术类型、手术持续时间和住院时间方面无统计学显著差异。与RDW水平低的患者相比，RDW水平高的患者合并症更多（p<0.05）。RDW水平高的患者全因死亡率更高，在3个月时（p<0.05）、6个月时（p<0.05）和12个月时（p<0.05）。
RDW与髋部骨折短期死亡率显著相关。RDW越高，死亡风险越高。
