Gidáli J, Fehér I
Int J Cell Cloning. 1985 May;3(3):149-55. doi: 10.1002/stem.5530030303.
The level of mobilizable 9-day colony-forming units (CFU-s), which represents a constant fraction of the normal mouse bone marrow CFU-s pool, was assayed in BDF1 mice with perturbed hemopoiesis (i.e., during increased turnover of CFU-s or increased CFU-s traffic after irradiation). After low-level irradiation, regeneration of the mobilizable CFU-s fraction was significantly slower than that of bone marrow CFU-s. Depletion of the mobilizable CFU-s pool was observed if a permanently increased outflow of CFU-s from the bone marrow was induced by endotoxin injection. After 40% withdrawal of the blood volume, the mobilizable CFU-s pool expanded marginally. Assuming that the level of mobilizable CFU-s is a consequence of production and outflow from the bone marrow compartment, changes in the pool size of mobilizable CFU-s may be a sensitive indicator of balanced or unbalanced hemopoiesis.
在造血功能受到干扰的BDF1小鼠（即CFU-s周转增加或照射后CFU-s流量增加期间）中，检测了可动员的9天集落形成单位（CFU-s）水平，其代表正常小鼠骨髓CFU-s池的恒定比例。低剂量照射后，可动员CFU-s部分的再生明显慢于骨髓CFU-s。如果通过内毒素注射诱导骨髓中CFU-s永久性流出增加，则可观察到可动员CFU-s池的消耗。在抽取40%血容量后，可动员CFU-s池略有扩大。假设可动员CFU-s的水平是骨髓区室产生和流出的结果，可动员CFU-s池大小的变化可能是造血平衡或不平衡的敏感指标。
