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澳大利亚肠外与肠内营养学会:关于再喂养综合征的共识声明

The Australasian Society of Parenteral and Enteral Nutrition: Consensus statements on refeeding syndrome.

作者信息

Matthews-Rensch Kylie, Blackwood Kirrilee, Lawlis Deborah, Breik Lina, McLean Cameron, Nguyen Truc, Phillips Sarah, Small Kimberly, Stewart Tim, Thatcher Amber, Venkat Leanne, Brodie Emily, Cleeve Brydie, Diamond Lauren, Ng Mei Yuen, Small Anna, Viner Smith Elizabeth, Asrani Varsha

机构信息

Dietetics and Foodservices, Royal Brisbane and Women's Hospital, Herston, Queensland, Australia.

Eating Disorders and Nutrition Research Group, School of Medicine, Western Sydney, New South Wales, Australia.

出版信息

Nutr Diet. 2025 Apr;82(2):128-142. doi: 10.1111/1747-0080.70003. Epub 2025 Mar 16.

Abstract

AIMS

This consensus statement document describes the recommendations of the Australasian Society of Parenteral and Enteral Nutrition regarding the identification and management of refeeding syndrome and refeeding syndrome risk.

METHODS

An expert working group completed a review of the literature to develop recommendations for the consensus statements. Review of the drafted consensus statements was undertaken by highly experienced clinicians.

RESULTS

The identification and management of refeeding syndrome requires a multidisciplinary approach. Actual refeeding syndrome is rare; however, all patients should be assessed for the risk of its development. Refeeding syndrome should only be diagnosed if the patient has had adequate nutrition intake (≥50% of estimated requirements), with electrolyte imbalances and clinical symptoms emerging after its commencement. Thiamin and multivitamin supplementation and regular electrolyte monitoring should be provided to all patients at risk of developing refeeding syndrome. There is no evidence that patients at risk of developing refeeding syndrome should be started at an initial lower enteral feeding rate than already recommended for checking tolerance to enteral feeds. Goal nutrition rates should be reached within 24-72 h for all routes of nutrition. Low electrolyte levels should be replaced as per local guidelines, with consideration given to the route of replacement.

CONCLUSION

These consensus statements are expected to provide guidance at a national level to improve the identification and management of refeeding syndrome and refeeding syndrome risk.

摘要

目的

本共识声明文件描述了澳大利亚和新西兰胃肠外与肠内营养学会关于再喂养综合征及其风险的识别与管理的建议。

方法

一个专家工作组完成了文献综述,以制定共识声明的建议。由经验丰富的临床医生对起草的共识声明进行审查。

结果

再喂养综合征的识别与管理需要多学科方法。实际的再喂养综合征很少见;然而,所有患者都应评估其发生风险。仅当患者有足够的营养摄入(≥估计需求量的50%),且在开始摄入后出现电解质失衡和临床症状时,才可诊断为再喂养综合征。应向所有有发生再喂养综合征风险的患者提供硫胺素和多种维生素补充剂,并定期监测电解质。没有证据表明,有发生再喂养综合征风险的患者应从低于已推荐的初始肠内喂养速率开始,以检查对肠内喂养的耐受性。所有营养途径均应在24 - 72小时内达到目标营养速率。应根据当地指南补充低水平电解质,并考虑补充途径。

结论

预计这些共识声明将在国家层面提供指导,以改善再喂养综合征及其风险的识别与管理。

相似文献

1
The Australasian Society of Parenteral and Enteral Nutrition: Consensus statements on refeeding syndrome.
Nutr Diet. 2025 Apr;82(2):128-142. doi: 10.1111/1747-0080.70003. Epub 2025 Mar 16.
3
ASPEN Consensus Recommendations for Refeeding Syndrome.
Nutr Clin Pract. 2020 Apr;35(2):178-195. doi: 10.1002/ncp.10474. Epub 2020 Mar 2.
4
Refeeding Syndrome in the Critically Ill: a Literature Review and Clinician's Guide.
Curr Gastroenterol Rep. 2019 Nov 22;21(11):58. doi: 10.1007/s11894-019-0724-3.
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[Refeeding syndrome: practical issues].
Rev Med Suisse. 2015 Oct 14;11(490):1886, 1888-91.
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[Chinese expert consensus on the application of electrolytes in parenteral nutrition (2024 edition)].
Zhonghua Yi Xue Za Zhi. 2024 Aug 27;104(33):3110-3122. doi: 10.3760/cma.j.cn112137-20240524-01181.
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[Refeeding syndrome].
Rev Med Interne. 2021 May;42(5):346-354. doi: 10.1016/j.revmed.2020.12.012. Epub 2021 Feb 3.
10
Refeeding syndrome: screening, incidence, and treatment during parenteral nutrition.
J Gastroenterol Hepatol. 2013 Dec;28 Suppl 4:113-7. doi: 10.1111/jgh.12345.

本文引用的文献

5
Incidence of hypophosphataemia after ICU admission in mechanically ventilated patients and its relationship with risk factors for refeeding syndrome.
Med Intensiva (Engl Ed). 2024 Jun;48(6):317-325. doi: 10.1016/j.medine.2024.01.004. Epub 2024 Feb 21.
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Association between energy delivery from parenteral nutrition and refeeding syndrome in hospitalized adults: A retrospective cohort study.
JPEN J Parenter Enteral Nutr. 2024 Apr;48(3):318-328. doi: 10.1002/jpen.2605. Epub 2024 Feb 11.
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Associations between low body weight, weight loss, and medical instability in adults with eating disorders.
Int J Eat Disord. 2024 Apr;57(4):869-878. doi: 10.1002/eat.24129. Epub 2024 Jan 6.
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Assessment of refeeding syndrome definitions and 30-day mortality in critically ill adults: A comparison study.
JPEN J Parenter Enteral Nutr. 2023 Nov;47(8):993-1002. doi: 10.1002/jpen.2560. Epub 2023 Oct 1.

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