Guo Xiuyan, Shi Chunhong
School of Nursing, Jiujiang University, Jiujiang, China.
School of Nursing, Xiangnan University, Chenzhou, China.
Front Public Health. 2025 Feb 28;13:1525580. doi: 10.3389/fpubh.2025.1525580. eCollection 2025.
Physical frailty is a common medical syndrome characterized by low muscle strength, low endurance, and reduced physiological function that leads to significantly negative health outcomes in older adults. This study investigated the risk variables among rural older adults in Hunan Province, China, and developed a physical frailty prediction model to inform policymaking to enhance their health and well-being.
This study was conducted from July 22 to September 3, 2022. A total of 291 participants were recruited using stratified cluster random sampling from five large villages in Hunan Province. Frailty screening was performed based on the Fatigue, Resistance, Ambulation, Illnesses, and Loss of Weight (FRAIL) scale, Geriatric Depression Scale 15-item version (GDS-15), Falls Efficacy Scale-International (FES-I), and Mini Nutrition Assessment-Short Form (MNA-SF). A logistic regression analysis was performed to identify the predictive factors for physical frailty and develop a physical frailty prediction model based on the area under the receiver operating characteristic (ROC) curve (AUC), sensitivity, specificity, and Youden index.
The physical frailty prevalence among rural older adults in Hunan Province was 21.31% ( = 62). Household income and expenditure [odds ratio (OR): 1.826, 95% confidence interval (CI): 1.142-2.918], physical exercise frequency (OR: 1.669, 95% CI: 1.137-2.451), depressive symptoms (OR: 9.069, 95% CI: 3.497-23.516), and fear of falling (OR: 3.135, 95% CI: 1.689-5.818) were identified as significant predictors of physical frailty in rural older individuals. The AUC for the frailty predictive model was 0.860 (95% CI: 0.805, 0.914). The sensitivity and specificity at the optimal cutoff value were 80.6 and 76.0%, respectively, with a Youden index of 0.566.
The prediction model constructed in this study demonstrated promise as a potential tool for evaluating physical frailty risk in older adults, which can contribute to healthcare providers' screenings for high-risk populations. Further multidimensional and experimental intervention studies should be conducted to prevent the occurrence and delay the progression of physical frailty in older adults.
身体虚弱是一种常见的医学综合征,其特征为肌肉力量低、耐力差和生理功能下降,会给老年人带来显著的负面健康后果。本研究调查了中国湖南省农村老年人中的风险变量,并开发了一种身体虚弱预测模型,以为政策制定提供信息,以增进他们的健康和福祉。
本研究于2022年7月22日至9月3日进行。采用分层整群随机抽样方法,从湖南省五个大村庄招募了291名参与者。基于疲劳、抵抗力、步行能力、疾病和体重减轻(FRAIL)量表、老年抑郁量表15项版本(GDS-15)、国际跌倒效能量表(FES-I)和简易营养评估简表(MNA-SF)进行虚弱筛查。进行逻辑回归分析以确定身体虚弱的预测因素,并基于受试者工作特征曲线(ROC)下面积(AUC)、敏感性、特异性和尤登指数开发身体虚弱预测模型。
湖南省农村老年人身体虚弱患病率为21.31%(n = 62)。家庭收支[比值比(OR):1.826,95%置信区间(CI):1.142 - 2.918]、体育锻炼频率(OR:1.669,95% CI:1.137 - 2.451)、抑郁症状(OR:9.069,95% CI:3.497 - 23.516)和害怕跌倒(OR:3.135,95% CI:1.689 - 5.818)被确定为农村老年个体身体虚弱的显著预测因素。虚弱预测模型的AUC为0.860(95% CI:0.805,0.914)。最佳截断值时的敏感性和特异性分别为80.6%和76.0%,尤登指数为0.566。
本研究构建的预测模型显示出有望成为评估老年人身体虚弱风险的潜在工具,有助于医疗保健提供者对高危人群进行筛查。应进一步开展多维度和实验性干预研究,以预防老年人身体虚弱的发生并延缓其进展。