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通过高危筛查和盆底生物反馈疗法预防直肠癌保肛手术后低位前切除综合征的研究。

Research on preventing low anterior resection syndrome following sphincter-preserving surgery for rectal cancer through high-risk screening and pelvic floor biofeedback therapy.

作者信息

Wang Wei, Cai Yulian, Peng Jie, Liu Liping, Feng Xiaomei, Wan Shuqin

机构信息

Jiangxi Cancer Hospital & Institute, the Second Affiliated Hospital of Nanchang Medical College, Nanchang, Jiangxi, People's Republic of China.

Department of Abdominal Surgery, Jiangxi Cancer Hospital, Nanchang, Jiangxi, People's Republic of China.

出版信息

Support Care Cancer. 2025 Mar 17;33(4):291. doi: 10.1007/s00520-025-09358-0.

DOI:10.1007/s00520-025-09358-0
PMID:40095142
Abstract

PURPOSE

This study aims to evaluate the effectiveness of high-risk screening combined with pelvic floor biofeedback therapy in preventing low anterior resection syndrome (LARS) after sphincter-preserving surgery (SPS) for rectal cancer.

METHODS

Forty-three patients who underwent SPS for rectal cancer at Jiangxi Cancer Hospital from January to December 2022 were assigned to the standard care group and received standard care plus pelvic floor biofeedback therapy. Forty-nine patients treated from January to December 2023 were designated as the high-risk screening group and received high-risk screening for LARS in addition to the standard care group's treatment protocol. LARS scores and incidence rates at 1, 3, and 6 months postoperatively, anorectal pressure values, quality of life scores at 3 and 9 months, and treatment adherence were compared between the two groups.

RESULTS

The high-risk screening group showed significantly lower LARS scores and incidence rates at all postoperative intervals compared to the standard care group. Additionally, the high-risk screening group demonstrated better anorectal pressure and quality of life scores and achieved higher treatment adherence, with statistically significant differences between groups (p < 0.05).

CONCLUSIONS

High-risk screening combined with targeted pelvic floor biofeedback therapy following SPS for rectal cancer can effectively prevent LARS and improve postoperative recovery quality.

摘要

目的

本研究旨在评估高危筛查联合盆底生物反馈疗法在直肠癌保肛手术后预防低位前切除综合征(LARS)的有效性。

方法

将2022年1月至12月在江西省肿瘤医院接受直肠癌保肛手术的43例患者分配至标准护理组,接受标准护理加盆底生物反馈疗法。将2023年1月至12月接受治疗的49例患者指定为高危筛查组,除接受标准护理组的治疗方案外,还接受LARS高危筛查。比较两组术后1、3和6个月时的LARS评分和发生率、肛门直肠压力值、3和9个月时的生活质量评分以及治疗依从性。

结果

与标准护理组相比,高危筛查组在所有术后时间点的LARS评分和发生率均显著降低。此外,高危筛查组的肛门直肠压力和生活质量评分更好,治疗依从性更高,组间差异具有统计学意义(p < 0.05)。

结论

直肠癌保肛手术后进行高危筛查联合针对性盆底生物反馈疗法可有效预防LARS并提高术后恢复质量。

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本文引用的文献

1
Cancer statistics, 2024.2024年癌症统计数据。
CA Cancer J Clin. 2024 Jan-Feb;74(1):12-49. doi: 10.3322/caac.21820. Epub 2024 Jan 17.
2
Risk factors for severe low anterior resection syndrome in patients with rectal cancer undergoing sphincter‑preserving resection: A systematic review and meta‑analysis.保留括约肌直肠癌切除术患者严重低位前切除综合征的危险因素:系统评价与荟萃分析
Oncol Lett. 2023 Nov 22;27(1):30. doi: 10.3892/ol.2023.14163. eCollection 2024 Jan.
3
Clinical Management of Low Anterior Resection Syndrome: Review of the Current Diagnosis and Treatment.
低位前切除综合征的临床管理:当前诊断与治疗的综述
Cancers (Basel). 2023 Oct 16;15(20):5011. doi: 10.3390/cancers15205011.
4
Low Anterior Resection Syndrome (LARS) after Surgery for Rectal Cancer: An Inevitable Price to Pay for Survival, or a Preventable Complication?直肠癌手术后的低位前切除综合征(LARS):是生存不可避免要付出的代价,还是可预防的并发症?
J Clin Med. 2023 Sep 14;12(18):5962. doi: 10.3390/jcm12185962.
5
Management of Low Anterior Resection Syndrome (LARS) Following Resection for Rectal Cancer.直肠癌切除术后低位前切除综合征(LARS)的管理
Cancers (Basel). 2023 Jan 27;15(3):778. doi: 10.3390/cancers15030778.
6
Risk factors for Low Anterior Resection Syndrome (LARS) in patients undergoing laparoscopic surgery for rectal cancer.直肠癌腹腔镜手术患者发生低位前切除综合征(LARS)的风险因素。
Surg Endosc. 2022 Aug;36(8):6059-6066. doi: 10.1007/s00464-021-09002-y. Epub 2022 Feb 8.
7
Low Anterior Resection Syndrome: Predisposing Factors and Treatment.低位前切除综合征:易患因素与治疗。
Surg Oncol. 2022 Aug;43:101691. doi: 10.1016/j.suronc.2021.101691. Epub 2021 Nov 25.
8
Using transanal irrigation in the management of low anterior resection syndrome: a service audit.经肛门直肠灌洗在低位前切除综合征治疗中的应用:服务质量审计。
Br J Nurs. 2021 Nov 25;30(21):1226-1230. doi: 10.12968/bjon.2021.30.21.1226.
9
Low anterior resection syndrome: can it be prevented?低位前切除综合征:可以预防吗?
Int J Colorectal Dis. 2021 Dec;36(12):2535-2552. doi: 10.1007/s00384-021-04008-3. Epub 2021 Aug 19.
10
The incidence and risk factors of low anterior resection syndrome (LARS) after sphincter-preserving surgery of rectal cancer: a systematic review and meta-analysis.直肠癌保肛手术后低位前切除综合征(LARS)的发生率及相关风险因素:系统评价与荟萃分析。
Support Care Cancer. 2021 Dec;29(12):7249-7258. doi: 10.1007/s00520-021-06326-2. Epub 2021 Jul 23.