Wang Wei, Cai Yulian, Peng Jie, Liu Liping, Feng Xiaomei, Wan Shuqin
Jiangxi Cancer Hospital & Institute, the Second Affiliated Hospital of Nanchang Medical College, Nanchang, Jiangxi, People's Republic of China.
Department of Abdominal Surgery, Jiangxi Cancer Hospital, Nanchang, Jiangxi, People's Republic of China.
Support Care Cancer. 2025 Mar 17;33(4):291. doi: 10.1007/s00520-025-09358-0.
This study aims to evaluate the effectiveness of high-risk screening combined with pelvic floor biofeedback therapy in preventing low anterior resection syndrome (LARS) after sphincter-preserving surgery (SPS) for rectal cancer.
Forty-three patients who underwent SPS for rectal cancer at Jiangxi Cancer Hospital from January to December 2022 were assigned to the standard care group and received standard care plus pelvic floor biofeedback therapy. Forty-nine patients treated from January to December 2023 were designated as the high-risk screening group and received high-risk screening for LARS in addition to the standard care group's treatment protocol. LARS scores and incidence rates at 1, 3, and 6 months postoperatively, anorectal pressure values, quality of life scores at 3 and 9 months, and treatment adherence were compared between the two groups.
The high-risk screening group showed significantly lower LARS scores and incidence rates at all postoperative intervals compared to the standard care group. Additionally, the high-risk screening group demonstrated better anorectal pressure and quality of life scores and achieved higher treatment adherence, with statistically significant differences between groups (p < 0.05).
High-risk screening combined with targeted pelvic floor biofeedback therapy following SPS for rectal cancer can effectively prevent LARS and improve postoperative recovery quality.
本研究旨在评估高危筛查联合盆底生物反馈疗法在直肠癌保肛手术后预防低位前切除综合征(LARS)的有效性。
将2022年1月至12月在江西省肿瘤医院接受直肠癌保肛手术的43例患者分配至标准护理组,接受标准护理加盆底生物反馈疗法。将2023年1月至12月接受治疗的49例患者指定为高危筛查组,除接受标准护理组的治疗方案外,还接受LARS高危筛查。比较两组术后1、3和6个月时的LARS评分和发生率、肛门直肠压力值、3和9个月时的生活质量评分以及治疗依从性。
与标准护理组相比,高危筛查组在所有术后时间点的LARS评分和发生率均显著降低。此外,高危筛查组的肛门直肠压力和生活质量评分更好,治疗依从性更高,组间差异具有统计学意义(p < 0.05)。
直肠癌保肛手术后进行高危筛查联合针对性盆底生物反馈疗法可有效预防LARS并提高术后恢复质量。