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胎儿氧合的安全边际。

Safety margin of fetal oxygenation.

作者信息

Meschia G

出版信息

J Reprod Med. 1985 Apr;30(4):308-11.

PMID:4009545
Abstract

The supply of O2 to fetal tissues depends upon a balance between factors that favor and hinder fetal oxygenation. Experiments in sheep have demonstrated that high rates of placental perfusion, high O2 affinity of fetal red cells and high rates of perfusion in fetal tissues compensate for an ineffective placental exchange system and for the circulatory arrangement by which fetal arterial blood is formed by mixing oxygenated umbilical venous blood with deoxygenated systemic venous blood. Under normal physiologic conditions the balance of the factors that influence fetal oxygenation provides the fetal lamb with an oxygen supply approximately twice the minimum level necessary to sustain fetal life.

摘要

向胎儿组织供应氧气取决于促进和阻碍胎儿氧合的各种因素之间的平衡。在绵羊身上进行的实验表明,高胎盘灌注率、胎儿红细胞的高氧亲和力以及胎儿组织的高灌注率弥补了无效的胎盘交换系统以及胎儿动脉血由含氧的脐静脉血与脱氧的体静脉血混合形成的循环结构。在正常生理条件下,影响胎儿氧合的各种因素的平衡为胎羊提供的氧气供应量约为维持胎儿生命所需最低水平的两倍。

相似文献

1
Safety margin of fetal oxygenation.胎儿氧合的安全边际。
J Reprod Med. 1985 Apr;30(4):308-11.
2
The transition from fetal to neonatal circulation: normal responses and implications for infants with heart disease.从胎儿循环到新生儿循环的转变:正常反应及其对患心脏病婴儿的影响。
Semin Perinatol. 1993 Apr;17(2):106-21.
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Distribution and recirculation of umbilical and systemic venous blood flow in fetal lambs during hypoxia.缺氧时胎羊脐静脉和体循环静脉血流的分布与再循环
J Dev Physiol. 1980 Feb-Apr;2(1-2):71-84.
4
Exclusion of the placenta during fetal cardiac bypass augments systemic flow and provides important information about the mechanism of placental injury.在胎儿体外循环期间排除胎盘可增加体循环血流量,并提供有关胎盘损伤机制的重要信息。
J Thorac Cardiovasc Surg. 1993 Mar;105(3):502-10; discussion 510-2.
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Blood circulation and oxygen transport in the fetal guinea pig.豚鼠胎儿的血液循环与氧气运输
J Dev Physiol. 1983 Jun;5(3):181-93.
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A comparison of sheep and human fetal oxygen delivery systems with use of a mathematical model.使用数学模型对绵羊和人类胎儿氧气输送系统进行的比较。
Am J Obstet Gynecol. 1985 Feb 15;151(4):449-55. doi: 10.1016/0002-9378(85)90268-6.
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Oxygen supply and fetal growth.氧气供应与胎儿生长
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Development and mechanisms of fetal hypoxia in severe fetal growth restriction.重度胎儿生长受限中胎儿缺氧的发生发展及机制
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[Parameters of maternal oxygen transport in risk pregnancies].[高危妊娠中母体氧运输的参数]
Z Geburtshilfe Perinatol. 1987 Jul-Aug;191(4):150-3.

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