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全肘关节置换术的下降趋势、患者人口统计学特征及并发症分析:全国性回顾性数据分析

Analyzing Declining Trends, Patient Demographics, and Complications in Total Elbow Arthroplasty: Nationwide Retrospective Data Analysis.

作者信息

Mahamid Assil, Jayyusi Fairoz, Laver Lior, Haj Yahya Mohammad, Wolff Gal, Yassin Ali, Behrbalk Eyal

机构信息

Department of Orthopedics, Hillel Yaffe Medical Center, Hadera 3820302, Israel.

Rappaport Faculty of Medicine, Technion University Hospital (Israel Institute of Technology), Haifa 3200003, Israel.

出版信息

J Clin Med. 2025 Feb 28;14(5):1645. doi: 10.3390/jcm14051645.

Abstract

Total elbow arthroplasty (TEA) was initially introduced for end-stage rheumatoid arthritis but has since expanded to include osteoarthritis and complex distal humerus fractures, particularly in elderly patients. Over the past two decades, TEA utilization trends have fluctuated, with a recent decline attributed to advancements in disease-modifying antirheumatic drugs. Despite its benefits, TEA presents a high complication rate, necessitating further investigation into clinical outcomes, costs, and postoperative management. This retrospective cohort study analyzed TEA procedures from 2016 to 2019 using the National Inpatient Sample (NIS) database. Patients were identified via ICD-10 codes, with elective procedures included to ensure homogeneity. This study examined temporal trends, patient demographics, comorbidities, complication rates, length of stay (LOS), and hospitalization costs. Statistical analyses included chi-square tests, -tests, and multivariate regression to assess associations between patient characteristics and outcomes. A total of 4110 TEA procedures were analyzed, revealing a 16% decline in annual volume from 2016 to 2019 ( = 0.012). The cohort had a mean age of 65.99 years, with a predominance of female (75.3%) and White (72.6%) patients. The median LOS was two days, and median hospitalization costs were USD 78,473 (IQR: 56,935-115,671 USD). The most prevalent complications included mechanical loosening (12.5%), blood loss anemia (10.6%), cardiac complications (5.7%), and prosthetic-related pain (3.3%). Multivariate analysis identified hypertension, anemia, and respiratory disease as significant predictors of adverse outcomes. TEA utilization has declined, likely due to medical advancements in rheumatoid arthritis management. The procedure remains associated with substantial complication rates, particularly in trauma-related cases. Findings highlight the importance of patient optimization, surgical expertise, and postoperative monitoring to improve outcomes.

摘要

全肘关节置换术(TEA)最初用于治疗终末期类风湿性关节炎,但后来其应用范围扩大到骨关节炎和复杂的肱骨远端骨折,尤其是老年患者。在过去二十年中,TEA的使用趋势波动不定,最近的下降归因于改善病情抗风湿药物的进展。尽管TEA有诸多益处,但它的并发症发生率很高,因此有必要进一步研究其临床结果、成本和术后管理。这项回顾性队列研究使用国家住院患者样本(NIS)数据库分析了2016年至2019年的TEA手术。通过国际疾病分类第十版(ICD-10)编码识别患者,并纳入择期手术以确保同质性。本研究考察了时间趋势、患者人口统计学特征、合并症、并发症发生率、住院时间(LOS)和住院费用。统计分析包括卡方检验、t检验和多变量回归,以评估患者特征与结果之间的关联。共分析了4110例TEA手术,结果显示2016年至2019年年手术量下降了16%(P = 0.012)。该队列的平均年龄为65.99岁,以女性(75.3%)和白人(72.6%)患者为主。中位住院时间为两天,中位住院费用为78473美元(四分位距:56935 - 115671美元)。最常见的并发症包括机械性松动(12.5%)、失血贫血(10.6%)、心脏并发症(5.7%)和假体相关疼痛(3.3%)。多变量分析确定高血压、贫血和呼吸系统疾病是不良结果的重要预测因素。TEA的使用有所下降,可能是由于类风湿性关节炎治疗方面的医学进展。该手术仍然与较高的并发症发生率相关,尤其是在创伤相关病例中。研究结果强调了优化患者情况、手术专业知识和术后监测对改善结果的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/da46/11900953/5a5152bfb1f1/jcm-14-01645-g001.jpg

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