Gandhavadi B, Melvin J L
J Ment Defic Res. 1985 Mar;29 ( Pt 1):49-54. doi: 10.1111/j.1365-2788.1985.tb00307.x.
Electrophysiological methods of studying the habituation of the blink reflex have been used, to document by objective means the lack of habituation of the blink reflex in mentally retarded adults. Habituation of the blink reflex to sets of stimuli with decreasing interstimulus duration, which is fixed in each set of stimuli, has been studied in normal human volunteers and mentally retarded subjects. Habituation of direct and indirect R2 has been poor or absent in the mentally retarded subjects. The habituation indices of mentally retarded subjects do not overlap the habituation indices of the normal volunteers. In significant numbers of retarded subjects no habituation of the indirect R2 (P less than 0.00001) and of direct R2 (P less than 0.0005) was noted. No significant difference in habituation of the direct R2 and indirect R2 is noted in normal volunteers.
已经采用了研究瞬目反射习惯化的电生理方法，以便通过客观手段证明智障成年人瞬目反射缺乏习惯化。在正常人类志愿者和智障受试者中，研究了瞬目反射对刺激组的习惯化情况，每组刺激中刺激间隔时间逐渐缩短且固定。在智障受试者中，直接R2和间接R2的习惯化较差或不存在。智障受试者的习惯化指数与正常志愿者的习惯化指数不重叠。在大量智障受试者中，未观察到间接R2（P<0.00001）和直接R2（P<0.0005）的习惯化。在正常志愿者中，直接R2和间接R2的习惯化没有显著差异。
