Ignacio Sabrina, Schlotthauer Jonatan, Sigrist Mirna, Volpedo Alejandra V, Thompson Gustavo A
Instituto de Investigaciones en Producción Animal (INPA), CONICET - Universidad de Buenos Aires, Av. Chorroarín 280 (C1427CWO), Buenos Aires, Argentina.
Facultad de Ciencias Veterinarias, Universidad de Buenos Aires, Buenos Aires, Argentina.
Arch Environ Contam Toxicol. 2025 Apr;88(3):253-276. doi: 10.1007/s00244-025-01123-y. Epub 2025 Mar 17.
Arsenic (As) is naturally occurring and is found in different forms, some of which are considered toxic to human health and frequently present in fishery resources. The aim of this work was to determine the contribution of toxic As species to the total As in muscle of two commercial fish species (Micropogonias furnieri and Urophycis brasiliensis) and to assess the toxicological risk associated with their consumption, considering different exposed groups. The total As concentrations found exceeded local guideline recommendations (> 1 mg kg wet weight), but the concentrations of the toxic As species were below this threshold. The inorganic As levels do not exceed the international guideline recommendations (0.03-0.15 μg kg bw per day of iAs). Both interspecific and intraspecific differences in As concentrations were found. Non-carcinogenic and carcinogenic risk values indicated that the exposed groups would not experience health risks through consumption of either fish species. However, due to the lack of an established safe consumption limit for iAs or As species worldwide, there are currently no legal tools to ensure that these fish species are safe for human consumption.
砷（As）是天然存在的，有不同的形态，其中一些被认为对人体健康有毒，并且经常存在于渔业资源中。这项工作的目的是确定有毒砷形态对两种商业鱼类（细纹绒须石首鱼和巴西深海鼬鳚）肌肉中总砷的贡献，并考虑不同暴露群体，评估食用这些鱼类相关的毒理学风险。所发现的总砷浓度超过了当地指导建议（>1毫克/千克湿重），但有毒砷形态的浓度低于该阈值。无机砷水平未超过国际指导建议（每天每千克体重摄入0.03 - 0.15微克无机砷）。发现了种间和种内砷浓度的差异。非致癌和致癌风险值表明，暴露群体通过食用这两种鱼类不会面临健康风险。然而，由于全球范围内缺乏针对无机砷或砷形态的既定安全消费限量，目前没有法律工具来确保这些鱼类对人类消费是安全的。
