Parrent Maurine, Filiu Elisa, Ozmen Tolga, Blanchard Odile, Pereira Ouarda, Mathelin Carole
Department of Medical Oncology, Centre Hospitalier Louis Pasteur, Colmar, France.
Department of Medicine, C. Centre Hospitalier de Sélestat-Obernai GHSO, Sélestat, France.
Eur J Breast Health. 2025 Mar 25;21(2):173-181. doi: 10.4274/ejbh.galenos.2025.2025-1-4. Epub 2025 Mar 18.
The risk of breast cancer in type 2 diabetic women is increased by 10-20%. Diabetic women have a higher risk of being diagnosed with advanced breast cancer and having complications with its treatments. In France, women aged between 50 and 74 years old are invited to undergo organized breast cancer screening (OBCS). The objective of this study was to evaluate OBCS participation in a large cohort of diabetic women.
Based on data from Social Security reimbursement databases, we studied OBCS participation rate of 50-74 years old diabetic women from the Grand-Est region (France) between 2020 and 2022, according to four age brackets and their geographical areas.
In 2020, among the 99,302 diabetic women, 16,340 (16.45%) underwent OBCS versus 24% in the general population. In 2021, among the 100,390 diabetic women, 20,914 (20.83%) underwent OBCS, versus 29% in the general population. In 2022, among the 101,694 diabetic women, 18,576 (18.27%) underwent OBCS, versus 24% in the general population. OBCS participation in 50-54 years old and 70-74 years olds were significantly lower (<0.0001 in 2020; <0.0001 in 2021; <0.0037 in 2022). There was a significant link between OBSC participation and geographical area (<0.0001).
The OBCS participation rate in women with type 2 diabetes was significantly lower than the general population, and associated with age and area. These findings suggest a need to inform patients and health care professionals about the higher risk of breast cancer in diabetic women to improve OBCS rates with the proven associated health benefits.
2型糖尿病女性患乳腺癌的风险增加了10%至20%。糖尿病女性被诊断为晚期乳腺癌及其治疗出现并发症的风险更高。在法国，年龄在50至74岁之间的女性被邀请参加有组织的乳腺癌筛查（OBCS）。本研究的目的是评估一大群糖尿病女性参加OBCS的情况。
基于社会保障报销数据库的数据，我们研究了2020年至2022年期间法国大东部地区50至74岁糖尿病女性的OBCS参与率，按照四个年龄组及其地理区域进行划分。
2020年，在99302名糖尿病女性中，16340人（16.45%）接受了OBCS，而普通人群的这一比例为24%。2021年，在100390名糖尿病女性中，20914人（20.83%）接受了OBCS，普通人群的比例为29%。2022年，在101694名糖尿病女性中，18576人（18.27%）接受了OBCS，普通人群的比例为24%。50至54岁以及70至74岁女性的OBCS参与率显著较低（2020年<0.0001；2021年<0.0001；2022年<0.0037）。OBCS参与情况与地理区域之间存在显著关联（<0.0001）。
2型糖尿病女性的OBCS参与率显著低于普通人群，且与年龄和地区有关。这些发现表明，有必要告知患者和医护人员糖尿病女性患乳腺癌的风险更高，以提高OBCS参与率，并带来已证实的相关健康益处。
