Palaniraman Ramamurthi
Department of Pediatrics, CR Child Health Centre, Tindivanam, Tamil Nadu, India.
Indian J Pediatr. 2025 May;92(5):511-518. doi: 10.1007/s12098-025-05470-5. Epub 2025 Mar 18.
Fever is the second most common symptom after respiratory complaints in pediatric practice, often causing parental anxiety despite usually resulting from self-limiting viral infections. Without localized symptoms, diagnosing hidden bacterial infections is challenging. Tropical regions like India present additional diagnostic challenges due to endemic diseases like malaria, dengue, and typhoid. This review provides an algorithmic approach to evaluate and manage short-duration fever in children, tailored to the Indian epidemiological context. The approach requires careful clinical assessment and consideration of bacterial and tropical etiologies. While most cases are self-limited viral infections, early identification of serious bacterial infections (SBI) is crucial in reducing morbidity and mortality. A structured approach is outlined, based on clinical symptoms, signs, age, and vaccination status. Children are divided into three groups: neonates (0-28 d), young infants (29-90 d), and older infants/toddlers (3-36 mo). Neonates and sick/toxic-appearing children with fever warrant immediate hospital admission for empirical antibiotics and diagnostic work-up. Management of young infants is stratified according to risk factors for SBI such as bacteremia, urinary tract infections (UTI), and pneumonia. Well-appearing older infants/toddlers are often managed as outpatients, with investigations tailored to specific clinical and epidemiological contexts.
在儿科临床中,发热是继呼吸道症状之后第二常见的症状,尽管通常由自限性病毒感染引起,但往往会导致家长焦虑。在没有局部症状的情况下,诊断隐匿性细菌感染具有挑战性。像印度这样的热带地区,由于疟疾、登革热和伤寒等地方病,带来了额外的诊断挑战。本综述提供了一种算法方法,用于评估和管理儿童短期发热,该方法是根据印度的流行病学背景量身定制的。该方法需要仔细的临床评估,并考虑细菌和热带病因。虽然大多数病例是自限性病毒感染,但早期识别严重细菌感染(SBI)对于降低发病率和死亡率至关重要。文中概述了一种基于临床症状、体征、年龄和疫苗接种状况的结构化方法。儿童分为三组:新生儿(0 - 28天)、小婴儿(29 - 90天)和大婴儿/幼儿(3 - 36个月)。发热的新生儿以及病情较重/有中毒表现的发热儿童需要立即住院,接受经验性抗生素治疗和诊断检查。小婴儿的管理根据SBI的危险因素进行分层,如菌血症、尿路感染(UTI)和肺炎。看起来状况良好的大婴儿/幼儿通常作为门诊患者进行管理,检查根据具体的临床和流行病学背景进行调整。