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揭示反复咯血的元凶:一例支气管迪厄拉富瓦病病例报告

Uncovering the culprit of recurrent hemoptysis: A case report of bronchial Dieulafoy disease.

作者信息

Qian Jiabin, Qian Yiheng, Chen Ruilin, Lv Xin

机构信息

Department of Pulmonary Medicine, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, China.

出版信息

Medicine (Baltimore). 2025 Mar 14;104(11):e41787. doi: 10.1097/MD.0000000000041787.

DOI:10.1097/MD.0000000000041787
PMID:40101047
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11922454/
Abstract

RATIONALE

Bronchial Dieulafoy disease (BDD) is caused by vascular malformations in the bronchial wall, which may rupture and bleed spontaneously or due to external factors. Bronchial artery embolization (BAE) is the treatment of choice.

PATIENTS CONCERNS

The patient in this case had a 15-year history of recurrent hemoptysis, which persisted despite aggressive medical treatment. Due to a stent in the iliac artery, conventional transfemoral BAE was not feasible.

DIAGNOSES

Fiberoptic bronchoscopy revealed exposed mucosal vessels with vascular malformations in the left upper lobe. Bronchial artery angiography further demonstrated arterial malformation, tortuosity, and hypertrophy at the lesion site, consistent with a diagnosis of BDD.

INTERVENTIONS

The patient successfully underwent BAE via a left distal radial artery puncture.

OUTCOMES

The patient's lesion was utterly resolved during the 1-year follow-up, with no disease progression.

LESSONS

Clinicians should consider BDD in cases of unexplained hemoptysis. BAE is the preferred treatment, and if conventional transfemoral access is not feasible, the radial artery can serve as an alternative approach. This case provides practical support for diversifying interventional techniques in BAE.

摘要

理论依据

支气管迪厄拉富瓦病(BDD)由支气管壁血管畸形引起,这些畸形可能自发破裂出血或因外部因素出血。支气管动脉栓塞术(BAE)是首选治疗方法。

患者情况

该病例患者有15年反复咯血病史,尽管积极药物治疗仍持续存在。由于髂动脉有支架,传统经股动脉BAE不可行。

诊断

纤维支气管镜检查显示左上叶有暴露的黏膜血管伴血管畸形。支气管动脉造影进一步显示病变部位动脉畸形、迂曲和增粗,符合BDD诊断。

干预措施

患者通过左桡动脉远端穿刺成功接受了BAE。

结果

患者病变在1年随访期间完全消退,无疾病进展。

经验教训

临床医生在不明原因咯血病例中应考虑BDD。BAE是首选治疗方法,若传统经股动脉途径不可行,桡动脉可作为替代途径。该病例为BAE介入技术多样化提供了实践支持。

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An unexpected bronchoscopic finding possibly induced by extracorporeal membrane oxygenation: A case report of bronchial Dieulafoy disease.体外膜肺氧合可能引发的支气管镜下意外发现:支气管杜氏病 1 例报告。
Medicine (Baltimore). 2024 Sep 6;103(36):e39636. doi: 10.1097/MD.0000000000039636.
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Bronchial Dieulafoy's disease: A series of seven cases with review of the literature.支气管迪厄拉富瓦病:七例病例系列并文献复习
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Efficacy of Bronchial Artery Embolization for Clinically Suspected Bronchial Dieulafoy's Disease.
支气管动脉栓塞术治疗临床疑似支气管迪厄拉富瓦病的疗效
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Recurrent hemoptysis in pediatric bronchial Dieulafoy's disease with inferior phrenic artery supply: A case report.小儿支气管迪厄拉富瓦病伴膈下动脉供血反复咯血1例报告
World J Clin Cases. 2023 Sep 16;11(26):6268-6273. doi: 10.12998/wjcc.v11.i26.6268.
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Dieulafoy's disease of the bronchus: rare but potentially fatal: a case report and a review of literature.支气管黏膜下恒径动脉破裂(Dieulafoy 病):罕见但潜在致命——1 例病例报告及文献复习
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