Afyouni Ahmad, Kotaich Jana, Sarout Sara, Chamoun Amarelle, Chkayban Georgia, El Hariri Saad, Baroud Tarek, Fatfat Adnan, El Masri Jad, Salemeh Pascale
Lebanese University, Faculty of Medical Sciences, Beirut, Lebanon; MEDICA Research Investigation, Beirut, Lebanon.
Lebanese University, Faculty of Medical Sciences, Beirut, Lebanon; MEDICA Research Investigation, Beirut, Lebanon; Institut National de Santé Publique d'Épidémiologie Clinique et de Toxicologie-Liban (INSPECT-LB), Beirut, Lebanon.
Transpl Immunol. 2025 May;90:102218. doi: 10.1016/j.trim.2025.102218. Epub 2025 Mar 16.
Immunotherapy is the concept of leveraging the immune system to treat diseases. Developing countries, including the Arab countries, have continued to lag in terms of biomedical research compared to other nations for several decades. Immunotherapy has been used in several fields, including cancer, transplantation, and vaccination. This article examined the activity and trend of immunotherapy research in the Arab world between 2000 and 2024.
The number of immunotherapy-related articles published by each Arab country, was assessed using the PubMed database between 2000 and 2024. Numbers were normalized with respect to each country's average population and average Gross Domestic Product (GDP).
Arab countries contributed to 1.73 % of total immunotherapy papers. The number of immunotherapy publications has grown from 2000 to 2022, then decreased in the past 2 years. In terms of publications per million persons, Qatar ranked first (130.08 per million persons), while in terms of publications per national GDP, Lebanon ranked first (11.09 per billion US dollars). MeSH keywords VOSviewer showed a focus on vaccination, COVID-19, COVID-19 vaccines, and transplantation conditioning in the Arab world.
This bibliometric analysis provides insight into the actualities and trends of immunotherapy research in the Arab world. This offers a general background for scientists, clinicians, funders, and decision-makers. Addressing the barriers that face immunotherapy research remains a cornerstone in the plan to improve the Arab world's output and contribution to this field.
免疫疗法是利用免疫系统治疗疾病的概念。包括阿拉伯国家在内的发展中国家在生物医学研究方面与其他国家相比,几十年来一直滞后。免疫疗法已应用于多个领域,包括癌症、移植和疫苗接种。本文研究了2000年至2024年阿拉伯世界免疫疗法研究的活动和趋势。
利用PubMed数据库评估2000年至2024年每个阿拉伯国家发表的免疫疗法相关文章数量。数据根据每个国家的平均人口和平均国内生产总值(GDP)进行了标准化处理。
阿拉伯国家的免疫疗法论文占总数的1.73%。免疫疗法出版物的数量从2000年到2022年有所增长,然后在过去两年有所下降。按每百万人口计算的出版物数量,卡塔尔排名第一(每百万人口130.08篇);按每国家GDP计算的出版物数量,黎巴嫩排名第一(每十亿美元11.09篇)。MeSH关键词VOSviewer显示,阿拉伯世界的研究重点是疫苗接种、COVID-19、COVID-19疫苗和移植预处理。
这项文献计量分析提供了对阿拉伯世界免疫疗法研究现状和趋势的洞察。这为科学家、临床医生、资助者和决策者提供了一个总体背景。解决免疫疗法研究面临的障碍仍然是提高阿拉伯世界在该领域产出和贡献计划的基石。