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糖尿病母亲所生早产儿的肺动脉血栓形成:一例报告

Pulmonary artery thrombosis in preterm infants born to a diabetic mother: a case report.

作者信息

Xiangyun Yin, Hongmin Xi, Liangliang Li, Weigang Liu, Lili Ma, Xianghong Li

机构信息

Department of the Affiliated Hospital of Qingdao University, Qingdao, China.

出版信息

J Med Case Rep. 2025 Mar 18;19(1):120. doi: 10.1186/s13256-025-05155-9.

Abstract

BACKGROUND

Pulmonary artery thrombosis in neonates is a rare entity. We describe a neonate with this diagnosis as well as his presentation, evaluation, and management. This case highlights the importance of cardiac ultrasound screening for neonates with high risk factors for pulmonary artery thrombosis without clinical symptoms, as it is not easily detected.

CASE PRESENTATION

Here, we present an unusual case of a Chinese premature infant, born to a diabetic mother, in whom thrombosis developed in the main pulmonary artery 12 days after an exploratory laparotomy. The preterm infant had no clinical manifestations of pulmonary artery thrombosis, which was found by reexamination of cardiac ultrasound before discharge; after treatment with low-molecular-weight heparin sodium, the embolus became smaller, and follow-up examination was conducted after discharge, and the baby is now developing well.

CONCLUSION

Pulmonary artery thrombosis is rare in newborns, and asymptomatic manifestations are even rarer in this age group. For newborns with high risk factors, early cardiac ultrasound screening is very important.

摘要

背景

新生儿肺动脉血栓形成是一种罕见疾病。我们描述了一名患有此诊断的新生儿及其临床表现、评估和治疗情况。该病例强调了对无临床症状但具有肺动脉血栓形成高危因素的新生儿进行心脏超声筛查的重要性,因为该病不易被发现。

病例报告

在此,我们呈现一例不寻常的病例,一名中国早产儿,其母亲患有糖尿病,该患儿在剖腹探查术后12天,主肺动脉发生血栓形成。该早产儿无肺动脉血栓形成的临床表现,在出院前复查心脏超声时被发现;经低分子肝素钠治疗后,栓子变小,出院后进行了随访检查,目前该婴儿发育良好。

结论

肺动脉血栓形成在新生儿中罕见,在该年龄组中无症状表现更为罕见。对于具有高危因素的新生儿,早期心脏超声筛查非常重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2e7/11916993/56be50b90126/13256_2025_5155_Fig1_HTML.jpg

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