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接受袋鼠式护理的早产儿的神经发育及相关因素:12个月随访

Neurodevelopment and Associated Factors in Preterm Infants Who Received Kangaroo Mother Care: A 12-Month Follow-Up.

作者信息

Ndjomo Gilles, Blairy Sylvie, Njiengwe Erero, Geurten Marie

机构信息

Laboratory of Behavioral Sciences and Applied Psychology (LAPSA), Douala University, Douala, Cameroon.

Psychology and Neuroscience of Cognition Research Unit (PsyNCog), University of Liège, Liège, Belgium.

出版信息

Acta Paediatr. 2025 Aug;114(8):1953-1962. doi: 10.1111/apa.70065. Epub 2025 Mar 19.

Abstract

AIM

Document the predictive factors for neurodevelopment up to the corrected age of 12 months for infants who received Kangaroo Mother Care (KMC).

METHODS

In total, 91 preterm infants and their 78 mothers were included in the study. Maternal symptoms, maternal compliance with KMC practices and infant characteristics and development were recorded.

RESULTS

Compared with formula and mixed milk, breast milk was associated with better developmental outcomes in locomotor (ß = 19.38, t = 4.21, p < 0.001), personal-social (ß = 19.39, t = 5.43, p < 0.001), hearing and speech (ß = 14.1, t = 3.6, p < 0.001), eye and hand coordination (ß = 17.31, t = 4.53, p < 0.001) and performance (ß = 11.21, t = 2.77, p = 0.006) subscales of the Griffith Mental Development Scales. However, the daily skin-to-skin contact (SSC) duration was negatively related to the locomotor (ß = -5.17, t = -2.04, p = 0.046), personal-social (ß = -4.92, t = -2.85, p = 0.007), hearing and speech (ß = -4.88, t = -2.63, p = 0.012), eye and hand coordination (ß = -4.77, t = -2.43, p = 0.018), and performance (ß = -5.67, t = -2.92, p = 0.007) subscales. The negative effect of SSC duration was moderated by the severity of maternal depressive symptoms.

CONCLUSION

Promoting breast milk and treating maternal depression could contribute to positive neurodevelopment in preterm infants.

摘要

目的

记录接受袋鼠式护理(KMC)的婴儿至矫正年龄12个月时神经发育的预测因素。

方法

本研究共纳入91名早产儿及其78名母亲。记录母亲的症状、母亲对KMC措施的依从性以及婴儿的特征和发育情况。

结果

与配方奶和混合奶相比,母乳喂养与格里菲斯心理发展量表的运动(β = 19.38,t = 4.21,p < 0.001)、个人社交(β = 19.39,t = 5.43,p < 0.001)、听力和语言(β = 14.1,t = 3.6,p < 0.001)、眼手协调(β = 17.31,t = 4.53,p < 0.001)和表现(β = 11.21,t = 2.77,p = 0.006)子量表中更好的发育结果相关。然而,每日皮肤接触(SSC)时长与运动(β = -5.17,t = -2.04,p = 0.046)、个人社交(β = -4.92,t = -2.85,p = 0.007)、听力和语言(β = -4.88,t = -2.63,p = 0.012)、眼手协调(β = -4.77,t = -2.43,p = 0.018)和表现(β = -5.67,t = -2.92,p = 0.007)子量表呈负相关。SSC时长的负面影响因母亲抑郁症状的严重程度而有所缓和。

结论

提倡母乳喂养和治疗母亲抑郁症有助于早产儿的积极神经发育。

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