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抗逆转录病毒治疗快速启动6年后的病毒学抑制及治疗留存情况评估

Assessment of Virologic Suppression and Retention in Care 6 Years After Rapid Initiation of Antiretroviral Therapy.

作者信息

Duggan Joan M, Himich Katie V, Sahloff Eric G

机构信息

Division of Infectious Diseases, Department of Medicine, College of Medicine and Life Sciences, University of Toledo, Toledo, Ohio, USA.

College of Pharmacy and Pharmaceutical Sciences, Department of Pharmacy Practice, University of Toledo, Toledo, Ohio, USA.

出版信息

Open Forum Infect Dis. 2025 Mar 5;12(3):ofaf122. doi: 10.1093/ofid/ofaf122. eCollection 2025 Mar.

DOI:10.1093/ofid/ofaf122
PMID:40103731
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11913637/
Abstract

In a single-center retrospective follow-up study, no difference in retention in care or virologic suppression was noted between rapid and delayed initiation of antiretroviral therapy at 6-year follow up in participants who were antiretroviral naive. Further study is needed to assess the long-term impact of rapidly starting antiretroviral therapy.

摘要

在一项单中心回顾性随访研究中，对于未接受过抗逆转录病毒治疗的参与者，在6年随访时，快速启动与延迟启动抗逆转录病毒治疗在治疗保留率或病毒学抑制方面未发现差异。需要进一步研究以评估快速启动抗逆转录病毒治疗的长期影响。

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本文引用的文献

[1]
Retention in care and viral suppression after same-day ART initiation: One-year outcomes of the SLATE I and II individually randomized clinical trials in South Africa.

J Int AIDS Soc. 2021-10

[2]
Time between diagnosis and achievement of virologic suppression in people living with HIV.

Am J Health Syst Pharm. 2021-6-29

[3]
RAPID antiretroviral therapy: high virologic suppression rates with immediate antiretroviral therapy initiation in a vulnerable urban clinic population.

AIDS. 2019-4-1

[4]
Implementation of a Rapid Entry Program Decreases Time to Viral Suppression Among Vulnerable Persons Living With HIV in the Southern United States.

Open Forum Infect Dis. 2018-6-28

[5]
Effect of Offering Same-Day ART vs Usual Health Facility Referral During Home-Based HIV Testing on Linkage to Care and Viral Suppression Among Adults With HIV in Lesotho: The CASCADE Randomized Clinical Trial.

JAMA. 2018-3-20

[6]
Same-day HIV testing with initiation of antiretroviral therapy versus standard care for persons living with HIV: A randomized unblinded trial.

PLoS Med. 2017-7-25

[7]
The Effect of Same-Day Observed Initiation of Antiretroviral Therapy on HIV Viral Load and Treatment Outcomes in a US Public Health Setting.

J Acquir Immune Defic Syndr. 2017-1-1

[8]
Initiating Antiretroviral Therapy for HIV at a Patient's First Clinic Visit: The RapIT Randomized Controlled Trial.

PLoS Med. 2016-5-10

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