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抗逆转录病毒治疗快速启动6年后的病毒学抑制及治疗留存情况评估

Assessment of Virologic Suppression and Retention in Care 6 Years After Rapid Initiation of Antiretroviral Therapy.

作者信息

Duggan Joan M, Himich Katie V, Sahloff Eric G

机构信息

Division of Infectious Diseases, Department of Medicine, College of Medicine and Life Sciences, University of Toledo, Toledo, Ohio, USA.

College of Pharmacy and Pharmaceutical Sciences, Department of Pharmacy Practice, University of Toledo, Toledo, Ohio, USA.

出版信息

Open Forum Infect Dis. 2025 Mar 5;12(3):ofaf122. doi: 10.1093/ofid/ofaf122. eCollection 2025 Mar.

DOI:10.1093/ofid/ofaf122
PMID:40103731
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11913637/
Abstract

In a single-center retrospective follow-up study, no difference in retention in care or virologic suppression was noted between rapid and delayed initiation of antiretroviral therapy at 6-year follow up in participants who were antiretroviral naive. Further study is needed to assess the long-term impact of rapidly starting antiretroviral therapy.

摘要

在一项单中心回顾性随访研究中,对于未接受过抗逆转录病毒治疗的参与者,在6年随访时,快速启动与延迟启动抗逆转录病毒治疗在治疗保留率或病毒学抑制方面未发现差异。需要进一步研究以评估快速启动抗逆转录病毒治疗的长期影响。

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本文引用的文献

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Retention in care and viral suppression after same-day ART initiation: One-year outcomes of the SLATE I and II individually randomized clinical trials in South Africa.南非 SLATE I 和 II 两项单独随机临床试验的一年随访结果:当日开始 ART 后患者的持续治疗和病毒抑制情况。
J Int AIDS Soc. 2021 Oct;24(10):e25825. doi: 10.1002/jia2.25825.
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Time between diagnosis and achievement of virologic suppression in people living with HIV.HIV感染者从诊断到实现病毒学抑制的时间。
Am J Health Syst Pharm. 2021 Jun 29. doi: 10.1093/ajhp/zxab269.
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RAPID antiretroviral therapy: high virologic suppression rates with immediate antiretroviral therapy initiation in a vulnerable urban clinic population.快速抗逆转录病毒治疗:在一个脆弱的城市诊所人群中,立即开始抗逆转录病毒治疗可实现高病毒学抑制率。
AIDS. 2019 Apr 1;33(5):825-832. doi: 10.1097/QAD.0000000000002124.
4
Implementation of a Rapid Entry Program Decreases Time to Viral Suppression Among Vulnerable Persons Living With HIV in the Southern United States.实施快速进入计划可缩短美国南部弱势HIV感染者实现病毒抑制的时间。
Open Forum Infect Dis. 2018 Jun 28;5(6):ofy104. doi: 10.1093/ofid/ofy104. eCollection 2018 Jun.
5
Effect of Offering Same-Day ART vs Usual Health Facility Referral During Home-Based HIV Testing on Linkage to Care and Viral Suppression Among Adults With HIV in Lesotho: The CASCADE Randomized Clinical Trial.莱索托成人居家HIV检测期间提供当日抗逆转录病毒治疗(ART)与常规医疗机构转诊对HIV感染者护理衔接和病毒抑制的影响:CASCADE随机临床试验
JAMA. 2018 Mar 20;319(11):1103-1112. doi: 10.1001/jama.2018.1818.
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The Effect of Same-Day Observed Initiation of Antiretroviral Therapy on HIV Viral Load and Treatment Outcomes in a US Public Health Setting.美国公共卫生环境下当日观察性启动抗逆转录病毒疗法对HIV病毒载量及治疗结果的影响
J Acquir Immune Defic Syndr. 2017 Jan 1;74(1):44-51. doi: 10.1097/QAI.0000000000001134.
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