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静脉-静脉体外膜肺氧合中的抗凝

Anticoagulation in venovenous extracorporeal membrane oxygenation.

作者信息

Jung Carolin, Stueber Thomas, Mirus Martin, Heubner Lars, Spieth Peter Markus

机构信息

Department of Anesthesiology and Intensive Care Medicine, Hannover Medical School, Hannover, Germany.

Department of Anesthesiology and Intensive Care Medicine, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany.

出版信息

Front Med (Lausanne). 2025 Mar 4;12:1530411. doi: 10.3389/fmed.2025.1530411. eCollection 2025.

Abstract

Venovenous extracorporeal membrane oxygenation (VV-ECMO) is a lifesaving therapy in severe acute respiratory distress syndrome (ARDS). Unfortunately, bleeding and thrombotic complications occur regularly due to coagulation disorders associated with the device, the underlying disease, and the anticoagulation management. To facilitate a personalized approach to hemostasis in individuals receiving ECMO support, it is essential to assess the coagulative state of the patient while simultaneously taking into account the underlying medical condition and administered therapies.

摘要

静脉-静脉体外膜肺氧合(VV-ECMO)是治疗严重急性呼吸窘迫综合征(ARDS)的一种挽救生命的疗法。不幸的是,由于与该设备、基础疾病及抗凝管理相关的凝血功能障碍,出血和血栓形成并发症经常发生。为了便于对接受ECMO支持的个体采取个性化止血方法,在考虑基础疾病状况和所给予治疗的同时评估患者的凝血状态至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df74/11913846/427ae4c5e9f3/fmed-12-1530411-g001.jpg

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