Aljohani Maher, Alfetayeh Asma, Alwasaidi Turki
Pathology, Prince Mohammed Bin Abdul Aziz Hospital (PMBAH) Ministry of National Guard Health Affairs (MNGHA), Madinah, SAU.
Hematology, Prince Mohammed Bin Abdul Aziz Hospital (PMBAH) Ministry of National Guard Health Affairs (MNGHA), Madinah, SAU.
Cureus. 2025 Feb 16;17(2):e79076. doi: 10.7759/cureus.79076. eCollection 2025 Feb.
This case report highlights a rare instance of pseudo-neutropenia involving in vitro alterations in neutrophils in a 67-year-old male with relapsed idiopathic thrombocytopenic purpura (ITP). Pseudo-neutropenia, also known as spurious neutropenia, refers to in vitro changes in neutrophil counts that do not accurately reflect the patient's clinical condition. This patient also exhibited pseudo-thrombocytopenia and cold agglutination in vitro. This phenomenon is often induced by the anticoagulant ethylenediaminetetraacetic acid (EDTA) or the presence of cold agglutinins or combined with a medication reaction.
本病例报告重点介绍了一名67岁复发性特发性血小板减少性紫癜(ITP)男性患者出现的罕见假性中性粒细胞减少症,该病症涉及中性粒细胞的体外改变。假性中性粒细胞减少症,也称为假性嗜中性白血球减少症,是指中性粒细胞计数的体外变化,不能准确反映患者的临床状况。该患者在体外还表现出假性血小板减少症和冷凝集现象。这种现象通常由抗凝剂乙二胺四乙酸(EDTA)、冷凝集素的存在或与药物反应共同引起。