O'Rourke I C
Med J Aust. 1985 Jul 8;143(1):13-6. doi: 10.5694/j.1326-5377.1985.tb122759.x.
A prospective study of surgery for peptic ulcer was undertaken to assess the current results of surgery in the so-called "post-cimetidine" era. Over a five-year period, 125 patients had undergone surgery; 82 parietal cell vagotomies, 10 vagotomy and drainage procedures, 10 Billroth I gastrectomies, 7 Billroth II gastrectomies, and 15 vagotomy and antrectomy procedures were performed. There were no postoperative deaths. Overall, the outcome was satisfactory in 92 patients, less than satisfactory in 13, and was considered a failure in 14, either because of recurrent ulceration (8%) or because of postoperative sequelae. The recurrence rate after parietal cell vagotomy was 5%. There was no difference in the recurrence rate after parietal cell vagotomy between women and men, but, overall, the results were less satisfactory in women after this operation. No significant difference in recurrence rate could be demonstrated between patients whose ulcers healed quickly after medical therapy and those whose ulcers did not heal.
开展了一项关于消化性溃疡手术的前瞻性研究，以评估在所谓“西咪替丁时代”手术的当前效果。在五年期间，125例患者接受了手术；实施了82例壁细胞迷走神经切断术、10例迷走神经切断术加引流术、10例毕罗一世胃切除术、7例毕罗二世胃切除术以及15例迷走神经切断术加胃窦切除术。术后无死亡病例。总体而言，92例患者的结果令人满意，13例不太令人满意，14例被认为手术失败，原因要么是溃疡复发（8%），要么是术后出现后遗症。壁细胞迷走神经切断术后的复发率为5%。壁细胞迷走神经切断术后，女性和男性的复发率没有差异，但总体而言，女性接受该手术后的结果不太令人满意。药物治疗后溃疡迅速愈合的患者与溃疡未愈合的患者之间，复发率没有显著差异。
