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黑人创伤性脑损伤后10年的整体功能轨迹:一项模型系统研究。

Trajectories of Global Functioning Over the 10 Years After Traumatic Brain Injury in Black Individuals: A Model System Study.

作者信息

Ohayagha Chimdindu, Xia Bridget, Jones Shawn C T, Klyce Daniel W, Arango-Lasprilla Juan Carlos, Perrin Paul B

机构信息

Department of Psychology, Virginia Commonwealth University, Richmond, VA.

School of Data Science, University of Virginia, Charlottesville, VA; Central Virginia Veterans Affairs Health Care System, Richmond, VA; Department of Physical Medicine and Rehabilitation, School of Medicine, Virginia Commonwealth University, Richmond, VA.

出版信息

Arch Phys Med Rehabil. 2025 Sep;106(9):1359-1366. doi: 10.1016/j.apmr.2025.03.034. Epub 2025 Mar 17.

Abstract

OBJECTIVE

This study examined longitudinal global functioning trajectories over the 10 years after traumatic brain injury (TBI) in a group of Black individuals, and demographic and injury-related predictors of those trajectories.

DESIGN

Participants completed follow-up data collections at 1, 2, 5, and 10 years after TBI and being discharged from acute rehabilitation.

SETTING

TBI Model System (TBIMS) hospitals.

PARTICIPANTS

This study included a subsample of Black individuals (N=2523) in the TBIMS National Database who had a completed global functioning scores at 1 or more follow-up time points.

INTERVENTIONS

Not applicable.

MAIN OUTCOME MEASURE

Glasgow Outcome Scale-Extended (GOS-E).

RESULTS

GOS-E scores across the full sample tended to increase slightly between years 1 and 2 and then plateaued for the successive years such that a quadratic, or U-shaped, trend best fit the data. Younger age (P<.001), higher level of education (P<.001), private insurance (P=.007), and shorter posttraumatic amnesia (PTA) duration (P<.001) were significant predictors of higher GOS-E trajectories. There was also a significant time × age effect (P<.001), such that younger adults improved slightly over the first 5 years and plateaued between years 5 and 10 relative to a general decline for older adults.

CONCLUSIONS

These findings suggest that age, education, insurance status, and PTA are important predictors of long-term global functional outcomes for Black individuals with TBI. Identifying baseline risk factors for Black individuals who may experience lower global functioning trajectories can inform development of targeted interventions and be a first step in working to reduce health disparities in functional outcomes in this group.

摘要

目的

本研究调查了一组黑人个体在创伤性脑损伤(TBI)后10年的纵向整体功能轨迹,以及这些轨迹的人口统计学和损伤相关预测因素。

设计

参与者在TBI后1年、2年、5年和10年以及从急性康复出院时完成随访数据收集。

设置

TBI模型系统(TBIMS)医院。

参与者

本研究包括TBIMS国家数据库中的黑人个体子样本(N = 2523),他们在1个或更多随访时间点有完整的整体功能评分。

干预措施

不适用。

主要结局指标

扩展格拉斯哥预后量表(GOS-E)。

结果

整个样本的GOS-E评分在第1年和第2年之间倾向于略有增加,然后在随后几年趋于平稳,因此二次曲线或U形趋势最符合数据。年龄较小(P <.001)、教育水平较高(P <.001)、有私人保险(P =.007)和创伤后遗忘(PTA)持续时间较短(P <.001)是较高GOS-E轨迹的显著预测因素。还存在显著的时间×年龄效应(P <.001),即较年轻的成年人在最初5年略有改善,在5年至10年之间趋于平稳,而老年人则普遍下降。

结论

这些发现表明,年龄、教育、保险状况和PTA是TBI黑人个体长期整体功能结局的重要预测因素。识别可能经历较低整体功能轨迹的黑人个体的基线风险因素,可以为制定有针对性的干预措施提供信息,并成为努力减少该群体功能结局健康差距的第一步。

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