Nagahata Tomomi, Okuda Nagako, Tanno Kozo, Yonekura Yuki, Higashiyama Aya, Taniguchi Hirokazu, Kosami Koki, Okayama Akira
Division of Applied Life Sciences, Graduate School of Life and Environmental Sciences, Kyoto Prefectural University, 1-5 Hangi-cho, Shimogamo, Sakyo-ku, Kyoto, 606-8522, Japan.
Department of Hygiene and Preventive Medicine, Iwate Medical University, 1-1-1 Idaidori, Yahaba-cho, Shiwa-gun, Iwate, 028-3694, Japan.
Hypertens Res. 2025 Mar 19. doi: 10.1038/s41440-025-02187-y.
We examined the effect of sex on the relationship between obesity and hypertension among Japanese people, who generally have a lower prevalence of obesity than Westerners. We analyzed the results of specific health checkups for Japanese aged 40-74 years (688,306 men and 891,191 women) obtained in 2011. The participants were divided into four age groups (40-49, 50-59, 60-69, and 70-74 years) and five body mass index (BMI) categories (≤ 24.9 [non-overweight/obesity], 25.0-26.9 and 27.0-29.9 [overweight], 30.0-34.9 and ≥ 35.0 kg/m [obesity]). The odds ratio for hypertension in each BMI category was calculated using normal weight as the reference. The prevalence of hypertension was 26.8%-65.5% for men and 17.6%-53.6% for women in the overweight or obesity categories in the 40-49 age group, and 72.0%-88.7% for men and 70.1%-90.6% for women in the 70-74 age group. In women aged 40-49, the prevalence of hypertension in each BMI category was approximately 10% lower than that in men, but there was almost no difference between men and women in the 70-74 age group. On the other hand, the odds ratio for hypertension was higher in women than in men across all BMI categories and age groups. A stronger relationship between obesity and hypertension was observed in women than in men in all age groups. Japanese women have not been the target of studies for obesity, but more attention should be paid to Japanese women with obesity.
我们研究了性别对日本人肥胖与高血压之间关系的影响，日本人的肥胖患病率通常低于西方人。我们分析了2011年对40 - 74岁日本人（688,306名男性和891,191名女性）进行的特定健康检查结果。参与者被分为四个年龄组（40 - 49岁、50 - 59岁、60 - 69岁和70 - 74岁）以及五个体重指数（BMI）类别（≤24.9[非超重/肥胖]、25.0 - 26.9和27.0 - 29.9[超重]、30.0 - 34.9和≥35.0 kg/m²[肥胖]）。以正常体重为参照，计算每个BMI类别中高血压的比值比。在40 - 49岁年龄组的超重或肥胖类别中，男性高血压患病率为26.8% - 65.5%，女性为17.6% - 53.6%；在70 - 74岁年龄组中，男性为72.0% - 88.7%，女性为70.1% - 90.6%。在40 - 49岁的女性中，每个BMI类别中的高血压患病率比男性低约10%，但在70 - 74岁年龄组中，男性和女性之间几乎没有差异。另一方面，在所有BMI类别和年龄组中，女性高血压的比值比高于男性。在所有年龄组中，女性肥胖与高血压之间的关系比男性更强。日本女性尚未成为肥胖研究的对象，但应更多关注肥胖的日本女性。
